ENSA

Gene Symbol	ENSA
Entrez Gene	2029
Alt Symbol	ARPP-19e
Species	Human
Gene Type	protein-coding
Description	endosulfine alpha
Other Description	alpha-endosulfine
Swissprots	Q6FHW0 Q5T5H2 Q6VUC9 Q6VUD1 Q6VUC8 Q6NUL2 Q6IAM4 Q6VUC7 E9PB69 Q9NRZ0 Q6VUD0 Q68D48 Q6VUC6 O43768 A8K1Z9
Accessions	AAQ73827 AAQ73828 AAQ73829 AAQ73830 AAQ73831 AAQ73832 CAB65125 EAW53528 EAW53529 EAW53530 EAW53531 EAW53532 EAW53533 O43768 AF067170 AAD32454 AF157509 AAF80340 AF157510 AAF80341 AK001981 BAG50998 AK057673 AK290064 BAF82753 AL711949 AW136940 AW409955 BC000436 AAH00436 BC004461 AAH04461 BC068544 AAH68544 BC069208 AAH69208 BE799496 BM771663 BM984677 BM993811 BQ005654 BQ883543 BU075511 BU858280 CB243574 CR457130 CAG33411 CR536578 CAG38815 CR749580 CAH18372 EU832303 ACE87560 EU832387 ACE86872 T78564 X99906 CAA68180 NM_004436 NP_004427 NM_207042 NP_996925 NM_207043 NP_996926 NM_207044 NP_996927 NM_207045 NP_996928 NM_207046 NP_996929 NM_207047 NP_996930 NM_207168 NP_997051
Function	Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents. {ECO:0000250, ECO:0000269|PubMed:9653196}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Tissue Specificity	Widely expressed with high levels in skeletal muscle and brain and lower levels in the pancreas. {ECO:0000269|PubMed:14728987, ECO:0000269|PubMed:9653196}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ENSA-Over-expression-Lysate - LY12530a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

ENSA overexpression lysate - LY404060 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ENSA overexpression lysate - LY404105 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ENSA overexpression lysate - LY417988 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ENSA overexpression lysate - LY430976 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ENSA 293 Cell Lysate - 403268 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

alpha Endosulfine Overexpression Lysate (Native) - NBL1-10279 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ENSA Over-expression Lysate Product - GWB-485C3E from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

alpha Endosulfine Overexpression Lysate (Native) - NBP2-04512 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human ENSA Knockdown Stable Cell Line - CSC-DC004952 from Creative biogene Category Cell Line Species Human

ENSA KO Cell Lysate-HEK293T - CLKO-0937 from Creative biogene Category Cell Lysate

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