| Gene Symbol | ENSA |
|---|---|
| Entrez Gene | 2029 |
| Alt Symbol | ARPP-19e |
| Species | Human |
| Gene Type | protein-coding |
| Description | endosulfine alpha |
| Other Description | alpha-endosulfine |
| Swissprots | Q6FHW0 Q5T5H2 Q6VUC9 Q6VUD1 Q6VUC8 Q6NUL2 Q6IAM4 Q6VUC7 E9PB69 Q9NRZ0 Q6VUD0 Q68D48 Q6VUC6 O43768 A8K1Z9 |
| Accessions | AAQ73827 AAQ73828 AAQ73829 AAQ73830 AAQ73831 AAQ73832 CAB65125 EAW53528 EAW53529 EAW53530 EAW53531 EAW53532 EAW53533 O43768 AF067170 AAD32454 AF157509 AAF80340 AF157510 AAF80341 AK001981 BAG50998 AK057673 AK290064 BAF82753 AL711949 AW136940 AW409955 BC000436 AAH00436 BC004461 AAH04461 BC068544 AAH68544 BC069208 AAH69208 BE799496 BM771663 BM984677 BM993811 BQ005654 BQ883543 BU075511 BU858280 CB243574 CR457130 CAG33411 CR536578 CAG38815 CR749580 CAH18372 EU832303 ACE87560 EU832387 ACE86872 T78564 X99906 CAA68180 NM_004436 NP_004427 NM_207042 NP_996925 NM_207043 NP_996926 NM_207044 NP_996927 NM_207045 NP_996928 NM_207046 NP_996929 NM_207047 NP_996930 NM_207168 NP_997051 |
| Function | Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents. {ECO:0000250, ECO:0000269|PubMed:9653196}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. |
| Tissue Specificity | Widely expressed with high levels in skeletal muscle and brain and lower levels in the pancreas. {ECO:0000269|PubMed:14728987, ECO:0000269|PubMed:9653196}. |
Human ENSA Gene cDNA Clone - orb143035 from Biorbyt
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Human-ENSA-cDNA-Clone - DC00204 from Abgent, a WuXi AppTec company
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ENSA - MBS1278004 from MyBioSource
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ENSA - MBS1274953 from MyBioSource
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ENSA - MBS1266767 from MyBioSource
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Human ENSA cDNA clone(NM_207042.1) - CDFG013734 from Creative Biomart
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Human ENSA cDNA clone(NM_207043.1) - CDFG013736 from Creative Biomart
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Human ENSA cDNA clone(NM_207044.1) - CDFG013737 from Creative Biomart
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Human ENSA cDNA clone(NM_207045.1) - CDFG013738 from Creative Biomart
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Human ENSA cDNA clone(NM_207046.1) - CDFG013739 from Creative Biomart
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Human ENSA cDNA clone(NM_207047.1) - CDFG013740 from Creative Biomart
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Human ENSA cDNA clone(NM_207168.1) - CDFG013759 from Creative Biomart
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Human ENSA cDNA clone(NM_004436.2) - CDFH005934 from Creative Biomart
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Human ENSA ORF Clone(NM_004436.2) - CDCL162395 from Creative Biomart
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Human ENSA ORF Clone(NM_004436.2) - CDCR288005 from Creative Biomart
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Human ENSA ORF Clone(NM_004436.2) - CDCR288006 from Creative Biomart
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Human ENSA ORF Clone(NM_207042.1) - CDCR327850 from Creative Biomart
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Human ENSA ORF Clone(NM_207042.1) - CDCR327851 from Creative Biomart
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Human ENSA ORF Clone(NM_207043.1) - CDCR327852 from Creative Biomart
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Human ENSA ORF Clone(NM_207043.1) - CDCR327853 from Creative Biomart
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Human ENSA ORF Clone(NM_207044.1) - CDCR327854 from Creative Biomart
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Human ENSA ORF Clone(NM_207044.1) - CDCR327855 from Creative Biomart
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Human ENSA ORF Clone(NM_207045.1) - CDCR327856 from Creative Biomart
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Human ENSA ORF Clone(NM_207045.1) - CDCR327857 from Creative Biomart
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Human ENSA ORF Clone(NM_207046.1) - CDCR327858 from Creative Biomart
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