| Gene Symbol | murE |
|---|---|
| Entrez Gene | 944791 |
| Alt Symbol | ECK0086, JW0083 |
| Species | Escherichia coli |
| Gene Type | protein-coding |
| Description | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-diaminopimelate ligase |
| Other Description | - |
| Swissprots | O07101 P22188 |
| Accessions | AAC73196 NP_414627 |
| Function | Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use many meso-diaminopimelate analogs as substrates, although much less efficiently, but not L-lysine. {ECO:0000269|PubMed:11124264, ECO:0000269|PubMed:2269304, ECO:0000269|PubMed:3905407}. |
| Subcellular Location | Cytoplasm {ECO:0000305}. |
| Top Pathways | Peptidoglycan biosynthesis, Lysine biosynthesis |