JAK1

Gene Symbol JAK1
Entrez Gene 3716
Alt Symbol JAK1A, JAK1B, JTK3
Species Human
Gene Type protein-coding
Description Janus kinase 1
Other Description tyrosine-protein kinase JAK1
Swissprots P23458 Q9UD26 Q59GQ2
Accessions CBG22571 EAX06547 EAX06548 P23458 AB209057 BAD92294 AB219242 BAE02826 AK128375 AK314257 BC009079 BC023604 AAH23604 BC062431 AAH62431 BC111401 AAI11402 BC132729 AAI32730 BX647675 BX648044 HQ628631 AER93381 M64174 AAA36527 XM_005270841 XP_005270898 XM_006710624 XP_006710687 XM_011541395 XP_011539697 NM_002227 NP_002218
Function Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor. {ECO:0000269|PubMed:11909529}.
Subcellular Location Endomembrane system; Peripheral membrane protein. Note=Wholly intracellular, possibly membrane associated.
Tissue Specificity Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue. {ECO:0000269|PubMed:7896447}.
Top Pathways Viral carcinogenesis, Pancreatic cancer, Signaling pathways regulating pluripotency of stem cells, Osteoclast differentiation, Epstein-Barr virus infection

Recombinant Human Jak1 Protein - H00003716-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Human Janus Kinase 1 Protein - abx067575 from Abbexa

Category Protein
Source E.coli
Species Human

JAK1 (phospho-Tyr1022) Blocking Peptide - abx062820 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Bovine, Chicken, Dog, Pig

JAK1 Blocking Peptide - abx062821 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Bovine, Chicken, Dog, Pig

Tyrosine-protein kinase JAK1 - H00003716-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Tyrosine-protein kinase JAK1 - H00003716-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Tyrosine-protein kinase JAK1 - P5568 from Acris Antibodies

Category Protein
Prices $1,010.00
Sizes 5 µg
Species Human

Janus Kinase 1 (JAK1), Human - 20-8524 from ARP American Research Products

Category Protein
Prices $501.00
Sizes 50 µg
Source E.coli
Species Human

JAK1 fusion protein - ag17940 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human
JAK1 fusion protein ag17940 SDS-PAGE

JAK1 fusion protein - ag18180 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Jak1 Active Human Recombinant Protein - GWB-PS3ABB from Genway Biotech

Category Protein
Prices $410.00
Sizes 10 µg
Species Human
Jak1 Active Human Recombinant Protein

JAK1 (Phospho-Tyr1022) Antibody Blocking Peptide - GWB-A94F30 from Genway Biotech

Category Peptide
Prices $138.00
Sizes 100 µg

Recombinant Human Janus Kinase 1, GST-tagged - JAK1-674H from Creative Biomart

Category Protein
Source Baculovirus.

Recombinant Human JAK1, GST-tagged - JAK1-670H from Creative Biomart

Category Protein
Source Sf9 cells
Species Human

Recombinant Human JAK1 - JAK1-249H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

Recombinant Janus Kinase 1 (JAK1) - RPC551Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Janus Kinase 1 (JAK1) - RPC551Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Janus Kinase 1 (JAK1) - RPC551Ra01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Rat

JAK1 Protein, Active, bulk - 14-918-K from EMD Millipore

Category Protein
Source N-terminal GST-tagged, recombinant, human JAK1 amino acids 866-end, expressed by baculovirus in Sf21 insect cells. Activated in vitro by auto-phosphorylation.
Species Human

JAK1 Protein, active, 10 µg - 14-918 from EMD Millipore

Category Protein
Prices $318.00
Sizes 10 µg also available in 250μg size as catalog # 14-918m and in bulk as catalog # 14-918-k.
Source N-terminal GST-tagged, recombinant, human JAK1 amino acids 866-end, expressed by baculovirus in Sf21 insect cells. Activated in vitro by auto-phosphorylation.

JAK1 Protein, active, 250 µg - 14-918M from EMD Millipore

Category Protein
Prices $2,544.00
Sizes 250 µg also available in 10μg size as catalog # 14-918 and in bulk as catalog # 14-918-k.
Source N-terminal GST-tagged, recombinant, human JAK1 amino acids 866-end, expressed by baculovirus in Sf21 insect cells. Activated in vitro by auto-phosphorylation.

JAK1 (pY1022) Blocking Peptide - CBP1626 from Cohesion Biosciences

Category Peptide
Prices $150.00, $450.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine, Chicken, Dog, Pig

JAK1 Blocking Peptide - CBP1627 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine, Chicken, Dog, Pig

JAK1 (I1016) Peptide - BS1193P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

p-JAK1 (Y1022) Peptide - BS4108P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl
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