CRLF2

Gene Symbol CRLF2
Entrez Gene 64109
Alt Symbol CRL2, CRLF2Y, TSLPR
Species Human
Gene Type protein-coding
Description cytokine receptor-like factor 2
Other Description IL-XR|TSLP receptor|cytokine receptor CRL2 precusor|thymic stromal lymphopoietin protein receptor|thymic stromal-derived lymphopoietin receptor
Swissprots Q9H5R3 Q5G7M1 Q9HC73 J3QKD1
Accessions CAL40435 CAL44819 CAV28560 CAX87028 CAZ78684 CBX74362 CBX78819 EAW98672 Q9HC73 AB052639 BAB60717 AF142570 AAG27923 AF338733 AAK60618 AK026800 BAB15557 AK223303 BAD97023 AK225583 AY775789 AAW66851 BC160055 AAI60055 XM_011545634 XP_011543936 XM_011545635 XP_011543937 XM_011546181 XP_011544483 XM_011546182 XP_011544484 NM_001012288 NP_001012288 NM_022148 NP_071431 NR_110830
Function Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system. {ECO:0000250, ECO:0000269|PubMed:11418668}.
Subcellular Location Isoform 1: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

TSLPR (Y-20) - sc-83871 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
TSLPR (Y-20): sc-83871. Western blot analysis of TSLPR expression in AML-193 whole cell lysate.

Anti-CRLF2 antibody - ab198922 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling CRLF2 with ab198922 at 1/60 dilution.

Anti-CRLF2 antibody - ab109626 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-CRLF2 antibody (ab109626) at 0.5 µg/mlLane 2 : Anti-CRLF2 antibody (ab109626) at 1 µg/mlLane 3 : Anti-CRLF2 antibody (ab109626) at 2 µg/mlLane 1 : Human liver tissue lysateLane 2 : Human liver tissue lysateLane 3 : Human liver tissue lysate

Anti-CRLF2 antibody - ab56373 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CRLF2 antibody [AT4E7] - ab177524 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT4E7
Lane 1 : Anti-CRLF2 antibody [AT4E7] (ab177524) at 1/500 dilutionLane 2 : Anti-CRLF2 antibody [AT4E7] (ab177524) at 1/1000 dilutionLane 3 : Anti-CRLF2 antibody [AT4E7] (ab177524) at 1/5000 dilutionLane 1 : HeLa cell line lysateLane 2 : HeLa cell line lysateLane 3 : HeLa cell line lysateLysates/proteins at 40 µg per lane.SecondaryGoat anti-mouse HRP conjugated antibodydeveloped using the ECL technique

Anti-CRLF2 antibody [EPR14603] - C-terminal - ab186427 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14603
All lanes : Anti-CRLF2 antibody [EPR14603] - C-terminal (ab186427) at 1/10000 dilutionLane 1 : Human fetal kidney lysateLane 2 : THP1 lysateLane 3 : HepG2 cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-CRLF2 antibody [IMG59N1H5] - ab168841 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone IMG59N1H5
All lanes : Anti-CRLF2 antibody [IMG59N1H5] (ab168841) at 5 µg/mlLane 1 : Partial recombinant protein at 0.1 µg/mlLane 2 : Human muscle lysate at 2 µg/mlLane 3 : Human liver lysate at 2 µg/ml

Anti-CRLF2 antibody [IMG59N3B7] - ab168847 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone IMG59N3B7
All lanes : Anti-CRLF2 antibody [IMG59N3B7] (ab168847) at 5 µg/mlLane 1 : CRLF2 partial recombinant protein at 0.10000000149 µg/mlLane 2 : Human liver lysate at 2 µg/ml

Anti-CRLF2 / TSLPR Antibody (clone 1B4) - LS-C40791 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1B4
Human monocyte-derived dendritic cells stained with purified 1B4, followed by biotinylated anti-mouse IgG and Sav-PE

Anti-CRLF2 / TSLPR Antibody (clone 8H8) - LS-C153299 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 8H8

Anti-CRLF2 / TSLPR Antibody (aa71-120) - LS-C116273 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CRLF2 antibody LS-C116273 Western blot of 721_B cell lysate.

Anti-CRLF2 / TSLPR Antibody (CF) - LS-C76383 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal
Staining of mouse splenocytes using LS-C76383 (filled histogram) or isotype control (open histogram).

Anti-CRLF2 / TSLPR Antibody (aa23-133) - LS-C307094 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CRLF2 / TSLPR Antibody (aa23-133, Azide-free) - LS-C330688 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CRLF2 / TSLPR Antibody (clone AT4E7) - LS-C200854 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone AT4E7
Western Blot: The cell lysate of HeLa (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CRLF2 antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Anti-CRLF2 / TSLPR Antibody (Internal) - LS-C34698 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Immunofluorescence of TSLP Receptor in Mouse Liver cells with TSLP Receptor antibody at 20 ug/ml.

Anti-CRLF2 / TSLPR Antibody (clone 8H8) IHC-plus™ - LS-B6755 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 8H8
Anti-CRLF2 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6755 concentration 10 ug/ml.

Anti-CRLF2 / TSLPR Antibody (aa30-232) - LS-C150093 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal
TSLP R in Human Liver. TSLP R was detected in immersion fixed paraffin-embedded sections of human liver using Goat Anti-Human TSLP R Antigen Affinity-purified Polyclonal Antibody at 15 ug/ml overnight at 4°C. Tissue was stained using Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

Anti-CRLF2 / TSLPR Antibody (Internal) IHC-plus™ - LS-B3211 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CRLF2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3211 concentration 5 ug/ml.

TSLP R/CRLF2 Antibody [Unconjugated] - AF981 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of human liver tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human TSLP R Antigen Affinity-purified Polyclonal Antibody (Catalog # AF981) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for TSLP R at approximately 50 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

TSLP R/CRLF2 Antibody - NBP2-29613 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

TSLP R/CRLF2 Antibody - NBP2-22384 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Polyclonal
Western Blot: TSLP R/CRLF2 Antibody [NBP2-22384] - Analysis of TSLPR in an A) partial recombinant protein (0.1 ug/ml) and B) human liver lysate (2ug/ml) using TSLPR antibody.

TSLP R/CRLF2 Antibody - NBP2-22383 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Polyclonal
Western Blot: TSLP R/CRLF2 Antibody [NBP2-22383] - Analysis of TSLPR in an A) partial recombinant protein (0.1 ug/ml), B) human muscle and C) liver lysate (2 ug/ml) using TSLPR antibody.

TSLP R/CRLF2 Antibody (59N5G4) - NBP2-27331 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 59N5G4
Western Blot: TSLP R/CRLF2 Antibody (59N5G4) [NBP2-27331] - Analysis of CRLF2 in an A) partial recombinant protein (0.1 ug/ml), B) human muscle and C) liver lysate (5 ug/ml) using CRLF2 antibody.

TSLP R/CRLF2 Antibody - NBP1-76794 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: TSLP R/CRLF2 Antibody [NBP1-76794] - Human liver tissue lysate with CRLF2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
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