CRLF2

Gene Symbol	CRLF2
Entrez Gene	64109
Alt Symbol	CRL2, CRLF2Y, TSLPR
Species	Human
Gene Type	protein-coding
Description	cytokine receptor-like factor 2
Other Description	IL-XR|TSLP receptor|cytokine receptor CRL2 precusor|thymic stromal lymphopoietin protein receptor|thymic stromal-derived lymphopoietin receptor
Swissprots	Q9H5R3 Q5G7M1 Q9HC73 J3QKD1
Accessions	CAL40435 CAL44819 CAV28560 CAX87028 CAZ78684 CBX74362 CBX78819 EAW98672 Q9HC73 AB052639 BAB60717 AF142570 AAG27923 AF338733 AAK60618 AK026800 BAB15557 AK223303 BAD97023 AK225583 AY775789 AAW66851 BC160055 AAI60055 XM_011545634 XP_011543936 XM_011545635 XP_011543937 XM_011546181 XP_011544483 XM_011546182 XP_011544484 NM_001012288 NP_001012288 NM_022148 NP_071431 NR_110830
Function	Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system. {ECO:0000250, ECO:0000269|PubMed:11418668}.
Subcellular Location	Isoform 1: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CRLF2 protein fragment - ab140729 from Abcam Category Protein Source E. coli Species Human

Human CRLF2 protein fragment - ab153480 from Abcam Category Protein Source Wheat germ Species Human

CRLF2 / TSLPR Antibody Blocking Peptide - LS-E30345 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CRLF2 / TSLPR Antibody Blocking Peptide - LS-E30346 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CRLF2 / TSLPR Antibody Blocking Peptide - LS-E16393 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TSLP R/CRLF2 Partial Recombinant Protein - H00064109-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human TSLP R/CRLF2 Protein - NBP2-22985 from Novus Biologicals Category Protein Prices $299.00 Sizes 100 µg Source E.coli Species Human

TSLP R/CRLF2 Blocking Peptide - NBP1-76794PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

CRLF2 Peptide - GTX85052-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Recombinant Human TSLP R Fc Chimera, CF - 981-TR-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human TSLPR protein - orb191109 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

CRLF2 Blocking Peptide - 33R-3132 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CRLF2 (23-231, His-tag) - AR50846PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CRLF2 (23-231, His-tag) - AR50846PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

CRLF2 - H00064109-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CRLF2 - H00064109-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CRLF2 Control Peptide - AP30966CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

CRLF2, 23-231aa, Human, His tag, E.coli - 01-P2022 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Recombinant Human CRLF2, MYC/DDK-tagged - CRLF2-75H from Creative Biomart Category Protein Source HEK293 cells Species Human

Recombinant Human CRLF2, Fc-tagged - CRLF2-76H from Creative Biomart Category Protein Source Mouse NSO Cells Species Human

Recombinant Human CRLF2, His-tagged - CRLF2-7578H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Cytokine receptor-like factor 2(CRLF2) - CSB-YP005983HU CSB-EP005983HU CSB-BP005983HU CSB-MP005983HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CRLF2, 23-231aa, Human, His tag, E.coli (Denatured) - ATGP2022 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Recombinant Human TSLP R Fc Chimera Protein, CF - 981-TR from R&D Systems Category Protein Prices $319.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Human TSLP R (Gly25-Lys231) Accession #Q9HC73 DIEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus Species Human

CRLF2 (transcript variant 1) - TP321190 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

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