| Gene Symbol |
ATG9A
|
| Entrez Gene |
79065
|
| Alt Symbol |
APG9L1, MGD3208, mATG9
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
autophagy related 9A
|
| Other Description |
APG9 autophagy 9-like 1|APG9-like 1|ATG9 autophagy related 9 homolog A|autophagy 9-like 1 protein|autophagy-related protein 9A
|
| Swissprots |
Q7Z3C6 Q9BVL5 Q3ZAQ6 Q9HAG7 Q7Z317 Q7Z320 Q8WU65 Q9H6L1 Q6P0N7 Q8NDK6
|
| Accessions |
EAW70706 EAW70707 Q7Z3C6 AK021732 BAB13882 AK025822 BAB15246 AK027448 BAB55119 AK056595 BAG51759 AK289755 BAF82444 AK302521 BAG63795 AK315553 AL833865 CAD38723 AM393801 CAL38676 BC001098 AAH01098 BC001206 BC021202 AAH21202 BC065534 AAH65534 BK004018 DAA05199 BP284912 BX537984 CAD97944 BX538192 CAD98061 BX538198 CAD98064 DC347583 NM_001077198 NP_001070666 NM_024085 NP_076990 NR_104255
|
| Function |
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H. {ECO:0000269|PubMed:16940348}.
|
| Subcellular Location |
Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation- induced redistribution depends on ULK1, ATG13, as well as SH3GLB1.
|