| Gene Symbol | ligA |
|---|---|
| Entrez Gene | 7130907 |
| Alt Symbol | - |
| Species | Escherichia coli |
| Gene Type | protein-coding |
| Description | NAD-dependent DNA ligase LigA |
| Other Description | - |
| Swissprots | B7MHR5 |
| Accessions | B7MHR5 CAR03873 YP_002392272 |
| Function | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. {ECO:0000255|HAMAP- Rule:MF_01588}. |
| Top Pathways | DNA replication, Nucleotide excision repair, Mismatch repair, Base excision repair |