| Gene Symbol | ftsI |
|---|---|
| Entrez Gene | 944799 |
| Alt Symbol | ECK0085, JW0082, pbpB, sep |
| Species | Escherichia coli |
| Gene Type | protein-coding |
| Description | transpeptidase involved in septal peptidoglycan synthesis; penicillin-binding protein 3 |
| Other Description | - |
| Swissprots | P0AD68 |
| Accessions | AAC73195 NP_414626 |
| Function | Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates. |
| Subcellular Location | Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein. |
| Top Pathways | Peptidoglycan biosynthesis, beta-Lactam resistance |