Gene Symbol |
AQP10
|
Entrez Gene |
89872
|
Alt Symbol |
AQPA_HUMAN
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
aquaporin 10
|
Other Description |
AQP-10|aquaglyceroporin-10|aquaporin-10|small intestine aquaporin
|
Swissprots |
Q5VYD3 Q8NG70 Q96PS8 Q5VYD4
|
Accessions |
EAW53209 EAW53210 EAW53211 Q96PS8 AB066105 BAB91223 AF159174 AAL25998 AK314993 BAG37489 BC069607 AAH69607 BC074896 AAH74896 BC074897 AAH74897 HQ448403 ADQ32883 XM_011510104 XP_011508406 NM_080429 NP_536354
|
Function |
Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol. {ECO:0000269|PubMed:11573934, ECO:0000269|PubMed:12084581}.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Expressed exclusively in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum.
|