| Gene Symbol | nrdA |
|---|---|
| Entrez Gene | 946612 |
| Alt Symbol | ECK2226, JW2228, dnaF |
| Species | Escherichia coli |
| Gene Type | protein-coding |
| Description | ribonucleoside-diphosphate reductase 1, alpha subunit |
| Other Description | - |
| Swissprots | P00452 P78088 P78177 |
| Accessions | AAC75294 NP_416737 |
| Function | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox- active cysteines. |
| Top Pathways | Purine metabolism, Pyrimidine metabolism |