| Gene Symbol | mug |
|---|---|
| Entrez Gene | 6058812 |
| Alt Symbol | - |
| Species | Escherichia coli |
| Gene Type | protein-coding |
| Description | G/U mismatch-specific DNA glycosylase |
| Other Description | - |
| Swissprots | B1XG73 |
| Accessions | ACB04153 B1XG73 YP_001731931 |
| Function | Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells. {ECO:0000255|HAMAP-Rule:MF_01956}. |
| Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01956}. |
| Top Pathways | Base excision repair |