| Gene Symbol | leuA |
|---|---|
| Entrez Gene | 1038600 |
| Alt Symbol | - |
| Species | Escherichia coli |
| Gene Type | protein-coding |
| Description | 2-isopropylmalate synthase |
| Other Description | - |
| Swissprots | Q8FL75 |
| Accessions | AAN78587 NP_752043 |
| Function | Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). {ECO:0000255|HAMAP-Rule:MF_01025}. |
| Top Pathways | Pyruvate metabolism, Valine, leucine and isoleucine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism |