| Gene Symbol | sufS |
|---|---|
| Entrez Gene | 5591454 |
| Alt Symbol | - |
| Species | Escherichia coli |
| Gene Type | protein-coding |
| Description | bifunctional cysteine desulfurase/selenocysteine lyase |
| Other Description | - |
| Swissprots | A8A0M6 |
| Accessions | A8A0M6 ABV06080 YP_001458463 |
| Function | Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo. {ECO:0000255|HAMAP- Rule:MF_01831}. |
| Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01831}. |
| Top Pathways | Selenocompound metabolism |