| Gene Symbol | SPCC825.02 |
|---|---|
| Entrez Gene | 2538725 |
| Alt Symbol | - |
| Species | S. pombe |
| Gene Type | protein-coding |
| Description | glucosidase II Gtb1 (predicted) |
| Other Description | - |
| Swissprots | P78894 Q9USH8 |
| Accessions | CAB58410 Q9USH8 NM_001023044 NP_588052 |
| Function | Subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins in the endoplasmic reticulum (ER). Specifically required for the cleavage of the final glucose. The subunit beta retains the catalytic subunit alpha in the ER. {ECO:0000269|PubMed:10464333, ECO:0000269|PubMed:19605557, ECO:0000269|PubMed:21471007}. |
| Subcellular Location | Endoplasmic reticulum {ECO:0000269|PubMed:16823372}. |
| Top Pathways | Protein processing in endoplasmic reticulum |