iscS

Gene Symbol iscS
Entrez Gene 7146623
Alt Symbol -
Species Escherichia coli
Gene Type protein-coding
Description cysteine desulfurase
Other Description -
Swissprots B7LDC2
Accessions B7LDC2 CAU98688 YP_002403824
Function Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate. {ECO:0000255|HAMAP-Rule:MF_00331}.
Subcellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00331}.
Top Pathways Sulfur relay system, Thiamine metabolism

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