| Gene Symbol | AGTR1 |
|---|---|
| Entrez Gene | 185 |
| Alt Symbol | AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, HAT1R |
| Species | Human |
| Gene Type | protein-coding |
| Description | angiotensin II receptor, type 1 |
| Other Description | type-1 angiotensin II receptor|type-1B angiotensin II receptor |
| Swissprots | Q13725 Q8TBK4 P30556 |
| Accessions | AAA35569 AAB35647 AAF70464 AAO65968 AAR03503 ABY87526 CAA77513 EAW78905 EAW78906 EAW78907 EAW78908 EAW78909 P30556 AI016286 AI240900 AK291541 BAF84230 AV651073 BC022447 AAH22447 BC068494 AAH68494 D13814 BAA02968 DA649921 DQ892388 ABM83314 DQ895601 ABM86527 M87290 AAA35535 M93394 AAA58370 S77410 AAB34644 X65699 CAA46621 NM_000685 NP_000676 NM_004835 NP_004826 NM_009585 NP_033611 NM_031850 NP_114038 NM_032049 NP_114438 |
| Function | Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Liver, lung, adrenal and adrenocortical adenomas. |
| Top Pathways | Calcium signaling pathway, Vascular smooth muscle contraction, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Renin-angiotensin system |