Gene Symbol | TTC5 |
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Entrez Gene | 91875 |
Alt Symbol | Strap |
Species | Human |
Gene Type | protein-coding |
Description | tetratricopeptide repeat domain 5 |
Other Description | TPR repeat protein 5|stress-responsive activator of p300|tetratricopeptide repeat protein 5 |
Swissprots | A8MQ18 Q96HF9 Q8N0Z6 |
Accessions | CAF86668 EAW66480 EAW66481 EAW66482 Q8N0Z6 AK074553 BAC11056 BC008647 AAH08647 BC030822 AAH30822 BC053538 AAH53538 BM998414 BX248066 CAD62359 BX640732 CAE45848 BX648584 DB051711 EU832467 ACE87639 HQ447721 ADQ32206 NM_138376 NP_612385 |
Function | Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Phosphorylation at Ser-203 results in nuclear localization, while unphosphorylated protein localizes to the cytoplasm. {ECO:0000250}. |
TTC5 (N-15) - sc-136948 from Santa Cruz Biotechnology
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TTC5 (C-13) - sc-136947 from Santa Cruz Biotechnology
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Anti-TTC5 antibody - ab36855 from Abcam
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Anti-TTC5 Antibody (aa372-401) - LS-C203868 from LifeSpan Bioscience
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Anti-TTC5 Antibody (C-Terminus) - LS-C81340 from LifeSpan Bioscience
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Anti-TTC5 Antibody (C-Terminus) - LS-C19472 from LifeSpan Bioscience
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Anti-TTC5 Antibody (C-Terminus) - LS-C10518 from LifeSpan Bioscience
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TTC5 Antibody - NBP1-53012 from Novus Biologicals
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TTC5 Antibody - NBP1-76636 from Novus Biologicals
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TTC5 Antibody - NBP1-92542 from Novus Biologicals
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TTC5 Antibody - H00091875-B01 from Novus Biologicals
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Anti-TTC5 antibody produced in rabbit - AV49004 from Sigma-Aldrich
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Anti-TTC5 antibody produced in rabbit - PRS3053 from Sigma-Aldrich
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TTC5 antibody - C-terminal region (ARP49004_P050) - ARP49004_P050 from Aviva Systems Biology
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TTC5-Antibody-C-term - AP20388b from Abgent, a WuXi AppTec company
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TTC5 Antibody - C-terminal region (OAAB17915) - OAAB17915 from Aviva Systems Biology
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TTC5 antibody - orb74485 from Biorbyt
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TTC5 Antibody - abx034731 from Abbexa
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TTC5 antibody - AP30970PU-N from Acris Antibodies
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TTC5 antibody - PAB12888 from Acris Antibodies
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Rabbit Anti-Human TTC5 (C-term) - 102-14728 from RayBiotech
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TTC5 Antibody - 3053 from ProSci
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TTC5 Antibody - 30-491 from ProSci
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TTC5 antibody (C-term) - STJ48161 from St John's Laboratory Ltd
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TTC5 antibody - 26112-1-AP from Proteintech Group
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