Gene Symbol | TTC5 |
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Entrez Gene | 91875 |
Alt Symbol | Strap |
Species | Human |
Gene Type | protein-coding |
Description | tetratricopeptide repeat domain 5 |
Other Description | TPR repeat protein 5|stress-responsive activator of p300|tetratricopeptide repeat protein 5 |
Swissprots | A8MQ18 Q96HF9 Q8N0Z6 |
Accessions | CAF86668 EAW66480 EAW66481 EAW66482 Q8N0Z6 AK074553 BAC11056 BC008647 AAH08647 BC030822 AAH30822 BC053538 AAH53538 BM998414 BX248066 CAD62359 BX640732 CAE45848 BX648584 DB051711 EU832467 ACE87639 HQ447721 ADQ32206 NM_138376 NP_612385 |
Function | Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Phosphorylation at Ser-203 results in nuclear localization, while unphosphorylated protein localizes to the cytoplasm. {ECO:0000250}. |
Active human TTC5 peptide - ab41841 from Abcam
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Human TTC5 full length protein - ab132432 from Abcam
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TTC5 Antibody Blocking Peptide - LS-E17727 from LifeSpan Bioscience
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TTC5 Antibody Blocking Peptide - LS-E30004 from LifeSpan Bioscience
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Recombinant Human TTC5 Protein - H00091875-P01 from Novus Biologicals
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TTC5 Peptide - NBP1-76636PEP from Novus Biologicals
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TTC5 Blocking Peptide - 33R-3213 from Fitzgerald
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TTC5 - H00091875-P01-10 from Acris Antibodies
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TTC5 - H00091875-P01-25 from Acris Antibodies
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TTC5 Control Peptide - AP30970CP-N from Acris Antibodies
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TTC5 Peptide - 3053P from ProSci
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TTC5 fusion protein - Ag23501 from Proteintech Group
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TTC5 fusion protein - Ag23523 from Proteintech Group
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Recombinant Human Tetratricopeptide repeat protein 5(TTC5) - CSB-YP822676HU CSB-EP822676HU CSB-BP822676HU CSB-MP822676HU from Cusabio
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Tetratricopeptide repeat protein 5 (TTC5), Recombinant Protein - MBS1281254 from MyBioSource
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TTC5 Protein - NBP1-92542PEP from Novus Biologicals
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TTC5-Blocking-Peptide-C-term - BP20388b from Abgent, a WuXi AppTec company
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TTC5 Peptide, Human - M34GP16811H from Creative Peptides
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TTC5 Recombinant Protein Antigen - NBP2-54927PEP from Novus Biologicals
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