Gene Symbol | TTC5 |
---|---|
Entrez Gene | 91875 |
Alt Symbol | Strap |
Species | Human |
Gene Type | protein-coding |
Description | tetratricopeptide repeat domain 5 |
Other Description | TPR repeat protein 5|stress-responsive activator of p300|tetratricopeptide repeat protein 5 |
Swissprots | A8MQ18 Q96HF9 Q8N0Z6 |
Accessions | CAF86668 EAW66480 EAW66481 EAW66482 Q8N0Z6 AK074553 BAC11056 BC008647 AAH08647 BC030822 AAH30822 BC053538 AAH53538 BM998414 BX248066 CAD62359 BX640732 CAE45848 BX648584 DB051711 EU832467 ACE87639 HQ447721 ADQ32206 NM_138376 NP_612385 |
Function | Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Phosphorylation at Ser-203 results in nuclear localization, while unphosphorylated protein localizes to the cytoplasm. {ECO:0000250}. |
TTC5 CRISPR/Cas9 KO Plasmid (h) - sc-408999 from Santa Cruz Biotechnology
|
||||||||
TTC5 HDR Plasmid (h) - sc-408999-HDR from Santa Cruz Biotechnology
|
||||||||
TTC5 Double Nickase Plasmid (h) - sc-408999-NIC from Santa Cruz Biotechnology
|
||||||||
TTC5 Double Nickase Plasmid (h2) - sc-408999-NIC-2 from Santa Cruz Biotechnology
|
||||||||
TTC5 CRISPR Activation Plasmid (h) - sc-408999-ACT from Santa Cruz Biotechnology
|
||||||||
TTC5 CRISPR Activation Plasmid (h2) - sc-408999-ACT-2 from Santa Cruz Biotechnology
|
||||||||
TTC5 Lentiviral Activation Particles (h) - sc-408999-LAC from Santa Cruz Biotechnology
|
||||||||
TTC5 Lentiviral Activation Particles (h2) - sc-408999-LAC-2 from Santa Cruz Biotechnology
|
||||||||
TTC5 siRNA (h) - sc-92262 from Santa Cruz Biotechnology
|
||||||||
TTC5 shRNA Plasmid (h) - sc-92262-SH from Santa Cruz Biotechnology
|
||||||||
TTC5 shRNA (h) Lentiviral Particles - sc-92262-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU015251 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN22183 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22183 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR04176 from Sigma-Aldrich
|
||||||||
TTC5 siRNA (Human) - CRJ4089 from Cohesion Biosciences
|
||||||||
TTC5 - MBS8200305 from MyBioSource
|
||||||||
shRNA set against Human TTC5 (NM_138376.2) - SHH437168 from Creative biogene
|
||||||||
Human TTC5 siRNA - orb274590 from Biorbyt
|
||||||||
TTC5 shRNA Plasmid (Human) - CHJ4089 from Cohesion Biosciences
|
||||||||
TTC5 miRNA 3'UTR clone - MiUTR3H-16459 from Creative biogene
|