| Gene Symbol | PFKM |
|---|---|
| Entrez Gene | 5213 |
| Alt Symbol | ATP-PFK, GSD7, PFK-1, PFK1, PFKA, PFKX, PPP1R122 |
| Species | Human |
| Gene Type | protein-coding |
| Description | phosphofructokinase, muscle |
| Other Description | 6-phosphofructo-1-kinase|6-phosphofructokinase type A|6-phosphofructokinase, muscle type|ATP-PFK|ATP-dependent 6-phosphofructokinase, muscle type|PFK-A|phosphofructo-1-kinase isozyme A|phosphofructokinase 1|phosphofructokinase, polypeptide X|phosphofructokinase-M|phosphohexokinase|protein phosphatase 1, regulatory subunit 122 |
| Swissprots | Q6ZTT1 Q16814 Q16815 J3KNX3 P08237 |
| Accessions | AAA36436 AAA82938 AAD14957 EAW57973 EAW57974 EAW57975 P08237 AK126020 AK126229 BAC86498 AK303681 BAG64674 AK308185 AK312284 BC000534 AAH00534 BC007798 AAH07798 BC012799 AAH12799 BC013298 AAH13298 BC021203 AAH21203 BU683561 BX537703 CAD97816 CR541698 CAG46499 D21861 D21862 DA525437 DA560355 DA761651 DA795106 DB081387 J05533 AAA79220 M26066 AAA60068 S72312 AAB31343 U24183 AAA91985 Y00698 CAA68692 XM_005268974 XP_005269031 XM_005268975 XP_005269032 XM_005268976 XP_005269033 XM_005268977 XP_005269034 XM_005268978 XP_005269035 XM_005268979 XP_005269036 XM_011538487 XP_011536789 XM_011538488 XP_011536790 NM_000289 NP_000280 NM_001166686 NP_001160158 NM_001166687 NP_001160159 NM_001166688 NP_001160160 |
| Function | Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. |
| Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03184}. |
| Top Pathways | Central carbon metabolism in cancer, AMPK signaling pathway, Glycolysis / Gluconeogenesis, RNA degradation, Pentose phosphate pathway |