| Gene Symbol |
CEP120
|
| Entrez Gene |
153241
|
| Alt Symbol |
CCDC100, SRTD13
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
centrosomal protein 120kDa
|
| Other Description |
centrosomal protein of 120 kDa|coiled-coil domain-containing protein 100
|
| Swissprots |
Q8N960 Q8IWB5 Q8NDE8 Q8N9Y0 Q6AW89 Q6AI52
|
| Accessions |
EAW48873 EAW48874 EAW48875 Q8N960 AK093409 BAC04155 AK095646 BAC04596 AK296999 BAG59537 AL833929 CAD38785 BC040527 BC144558 BX648687 CAH10561 CB854619 CR627324 CAH10371 DA508726 DB092908 XM_005271901 XP_005271958 XM_011543185 XP_011541487 XM_011543186 XP_011541488 NM_001166226 NP_001159698 NM_153223 NP_694955
|
| Function |
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo. {ECO:0000250}.
|