Gene Symbol | CEP120 |
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Entrez Gene | 153241 |
Alt Symbol | CCDC100, SRTD13 |
Species | Human |
Gene Type | protein-coding |
Description | centrosomal protein 120kDa |
Other Description | centrosomal protein of 120 kDa|coiled-coil domain-containing protein 100 |
Swissprots | Q8N960 Q8IWB5 Q8NDE8 Q8N9Y0 Q6AW89 Q6AI52 |
Accessions | EAW48873 EAW48874 EAW48875 Q8N960 AK093409 BAC04155 AK095646 BAC04596 AK296999 BAG59537 AL833929 CAD38785 BC040527 BC144558 BX648687 CAH10561 CB854619 CR627324 CAH10371 DA508726 DB092908 XM_005271901 XP_005271958 XM_011543185 XP_011541487 XM_011543186 XP_011541488 NM_001166226 NP_001159698 NM_153223 NP_694955 |
Function | Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo. {ECO:0000250}. |
CEP120 CRISPR/Cas9 KO Plasmid (h) - sc-406976 from Santa Cruz Biotechnology
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CEP120 HDR Plasmid (h) - sc-406976-HDR from Santa Cruz Biotechnology
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CEP120 Double Nickase Plasmid (h) - sc-406976-NIC from Santa Cruz Biotechnology
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CEP120 Double Nickase Plasmid (h2) - sc-406976-NIC-2 from Santa Cruz Biotechnology
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CEP120 CRISPR Activation Plasmid (h) - sc-406976-ACT from Santa Cruz Biotechnology
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CEP120 CRISPR Activation Plasmid (h2) - sc-406976-ACT-2 from Santa Cruz Biotechnology
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CEP120 Lentiviral Activation Particles (h) - sc-406976-LAC from Santa Cruz Biotechnology
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CEP120 Lentiviral Activation Particles (h2) - sc-406976-LAC-2 from Santa Cruz Biotechnology
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CEP120 siRNA (h) - sc-91885 from Santa Cruz Biotechnology
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CEP120 shRNA Plasmid (h) - sc-91885-SH from Santa Cruz Biotechnology
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CEP120 shRNA (h) Lentiviral Particles - sc-91885-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU067011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5958 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5958 from Sigma-Aldrich
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CEP120 siRNA (Human) - CRJ5762 from Cohesion Biosciences
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CEP120 - MBS8232909 from MyBioSource
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shRNA set against Human CEP120 (NM_153223.3) - SHH261797 from Creative biogene
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Human CEP120 siRNA - orb276263 from Biorbyt
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CEP120 shRNA Plasmid (Human) - CHJ5762 from Cohesion Biosciences
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CEP120 miRNA 3'UTR clone - MiUTR3H-12900 from Creative biogene
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CEP120 miRNA 3'UTR clone - MiUTR3H-12901 from Creative biogene
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