Gene Symbol |
SLC20A2
|
Entrez Gene |
518905
|
Alt Symbol |
-
|
Species |
Bovine
|
Gene Type |
protein-coding
|
Description |
solute carrier family 20 (phosphate transporter), member 2
|
Other Description |
phosphate transporter 2|piT-2|sodium-dependent phosphate transporter 2|solute carrier family 20 member 2
|
Swissprots |
A1A4I1
|
Accessions |
A1A4I1 DAA14446 BC126506 AAI26507 XM_005226113 XP_005226170 XM_005226114 XP_005226171 XM_010820335 XP_010818637 XM_010820336 XP_010818638 XM_010820337 XP_010818639 XM_010820338 XP_010818640 NM_001080280 NP_001073749
|
Function |
Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage calcification and vascular calcification. Functions as a retroviral receptor (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|