Gene Symbol | PPAP2C |
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Entrez Gene | 8612 |
Alt Symbol | LPP2, PAP-2c, PAP2-g |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidic acid phosphatase type 2C |
Other Description | PAP2-gamma|PAP2c|lipid phosphate phosphohydrolase 2|phosphatidate phosphohydrolase type 2c|phosphatidic acid phosphatase 2c|phosphatidic acid phosphohydrolase type 2c|type-2 phosphatidic acid phosphatase-gamma |
Swissprots | E9PAY8 A6NLV0 O43688 |
Accessions | EAW61207 EAW61208 EAW61209 O43688 AA428937 AB209696 BAD92933 AF035959 AAC15968 AF047760 AAC32104 AF056083 AAC25666 BC002806 AAH02806 BE615792 BG831889 BM050291 BM982485 BT007021 AAP35667 HY160303 XM_011528396 XP_011526698 NM_003712 NP_003703 NM_177526 NP_803545 NM_177543 NP_808211 |
Function | Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P). The relative catalytic efficiency is PA > C-1-P > LPA > S-1-P. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Found mainly in brain, pancreas and placenta. |
Top Pathways | Fc gamma R-mediated phagocytosis, Fat digestion and absorption, Choline metabolism in cancer, Ether lipid metabolism, Glycerolipid metabolism |
Human PPAP2C full length protein - ab160111 from Abcam
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Human PPAP2C protein fragment - ab160112 from Abcam
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PPAP2C Antibody Blocking Peptide - LS-E7106 from LifeSpan Bioscience
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Recombinant Human PPAP2C Protein - H00008612-P01 from Novus Biologicals
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Recombinant Human PPAP2C Protein - H00008612-Q01 from Novus Biologicals
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PPAP2C-Antibody-C-term-Blocking-Peptide - BP2799b from Abgent, a WuXi AppTec company
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PPAP2C-Antibody-N-term-Blocking-Peptide - BP2799a from Abgent, a WuXi AppTec company
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PAP2c peptide - orb73099 from Biorbyt
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PPAP2C / LPP2 - H00008612-P01-02 from Acris Antibodies
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PPAP2C / LPP2 - H00008612-Q01-10 from Acris Antibodies
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PPAP2C / LPP2 - H00008612-Q01-25 from Acris Antibodies
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PPAP2C fusion protein - ag0660 from Proteintech Group
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PPAP2C Peptide, Human - M34GP12167H from Creative Peptides
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PPAP2C Recombinant Protein Antigen - NBP2-31607PEP from Novus Biologicals
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Lipid phosphate phosphohydrolase 2 (PPAP2C), Recombinant Protein - MBS1207428 from MyBioSource
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Lipid phosphate phosphohydrolase 2 (PPAP2C), Recombinant Protein - MBS7026879 from MyBioSource
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