| Gene Symbol | NAT2 |
|---|---|
| Entrez Gene | 10 |
| Alt Symbol | AAC2, NAT-2, PNAT |
| Species | Human |
| Gene Type | protein-coding |
| Description | N-acetyltransferase 2 (arylamine N-acetyltransferase) |
| Other Description | N-acetyltransferase type 2|arylamide acetylase 2|arylamine N-acetyltransferase 2 |
| Swissprots | O60654 Q2MLE4 Q2MLK4 Q2MLF5 Q2MLK6 O43637 Q2MLG8 Q13146 O60655 Q86XS0 Q6LET4 Q86XS1 Q96T65 Q2MLJ6 P11245 Q96T64 Q9H220 Q2MLN7 Q16697 Q96KY8 |
| Accessions | AAA59905 AAA59906 AAA64584 AAA64585 AAA98976 AAC03773 AAC14117 AAC14118 AAG34181 AAK51710 AAK51711 AAO73561 AAO73562 AAP81164 ABC26032 ABC26033 ABC26034 ABC26035 ABC26036 ABC26037 ABC26038 ABC26039 ABC26040 ABC26041 ABC26042 ABC26043 ABC26044 ABC26045 ABC26046 ABC26047 ABC26048 ABC26049 ABC26050 ABC26051 ABC26052 ABC26053 ABC26054 ABC26055 ABC26056 ABC26057 ABC26058 ABC26059 ABC26060 ABC26061 ABC26062 ABC26063 ABC26064 ABC26065 ABC26066 ABC26067 ABC26068 ABC26069 ABC26070 ABC26071 ABC26072 ABC26073 ABC26074 ABC26075 ABC26076 ABC26077 ABC26078 ABC26079 ABC26080 ABC26081 ABC26082 ABC26083 ABC26084 ABC26085 ABC26086 ABC26087 ABC26088 ABC26089 ABC26090 ABC26091 ABC26092 ABC26093 ABC26094 ABC26095 ABC26096 ABC26097 ABC26098 ABC26099 ABC26100 ABC26101 ABC26102 ABC26103 ABC26104 ABC26105 ABC26106 ABC26107 ABC26108 ABC26109 ABC26110 ABC26111 ABC26112 ABC26113 ABC26114 ABC26115 ABC26116 ABC26117 ABC26118 ABC26119 ABC26120 ABC26121 ABC26122 ABC26123 ABC26124 ABC26125 ABC26126 ABC26127 ABC26128 ABC26129 ABC26130 ABC26131 ABC26132 ABC26133 ABC26134 ABC26135 ABC26136 ABC26137 ABC26138 ABC26139 ABC26140 ABC26141 ABC26142 ABC26143 ABC26144 ABC26145 ABC26146 ABC26147 ABC26148 ABC26149 ABC26150 ABC26151 ABC26152 ABC26153 ABC26154 ABC26155 ABC26156 ABC26157 ABC26158 ABC26159 ABC26160 ABC26161 ABC26162 ABC26163 ABC26164 ABC26165 ABC26166 ABC26167 ABC26168 ABC26169 ABC26170 ABC26171 ABC26172 ABC26173 ABC26174 ABC26175 ABC26176 ABC26177 ABC26178 ABC26179 ABC26180 ABC26181 ABC26182 ABC26183 ABC26184 ABC26185 ABC26186 ABC26187 ABC26188 ABC26189 ABC26190 ABC26191 ABF01136 ABF01137 ABF01138 ABF01139 ABF01140 ABF01141 ABF01142 ABF01143 ABF01144 ABF01145 ABF01146 ABF01147 ABF01148 ABF01149 ABF01150 ABF01151 ABF01152 ABF01153 ABF01154 ABF01155 ABF01156 ABF01157 ABF01158 ABF01159 ABF01160 ABF01161 ABF01162 ABF01163 ABF01164 ABF01165 ABF01166 ABF01167 ABF01168 ABF01169 ABF01170 ABF01171 ABF01172 ABF01173 ABF01174 ABF01175 ABF01176 ABF01177 ABF01178 ABF01179 ABF01180 ABF01181 ABF01182 ABF01183 ABF01184 ABF01185 ABF01186 ABF01187 ABF01188 ABF01189 ABF01190 ABF01191 ABF01192 ABF01193 ABF01194 ABF01195 ABF01196 ABF01197 ABF01198 ABF01199 ABF01200 ABF01201 ABF01202 ABF01203 ABF01204 ABF01205 ABF01206 ABF01207 ABF01208 ABF01209 ABF01210 ABF01211 ABF01212 ABF01213 ABF01214 ABF01215 ABF01216 ABF01217 ABF01218 ABF01219 ABF01220 ABF01221 ABF01222 ABF01223 ABF01224 ABF01225 ABF01226 ABF01227 ABF01228 ABF01229 ABF01230 ABF01231 ABF01232 ABF01233 ABF01234 ABF01235 ABF01236 ABF01237 ABF01238 ABF01239 ABF01240 ABF01241 ABF01242 ABF01243 ABF01244 ABF01245 ABF01246 ABF01247 ABF01248 ABF01249 ABF01250 ABF01251 ABF01252 ABF01253 ABF01254 ABF01255 ABF01256 ABF01257 ABF01258 ABF01259 ABF01260 ABF01261 ABF01262 ABF01263 ABF01264 ABF01265 ABF01266 ABF01267 ABF01268 ABF01269 ABF01270 ABF01271 ABF01272 ABF01273 ABF01274 ABF01275 ABF01276 ABF01277 ABF01278 ABF01279 ABF01280 ABF01281 ABF01282 ABF01283 ABF01284 ABF01285 ABF01286 ABF01287 ABF01288 ABF01289 ABF01290 ABF01291 ABF01292 ABF01293 ABF01294 ABF01295 ABF01296 ABF01297 ABF01298 ABF01299 ABF01300 ABF01301 ABF01302 ABF01303 ABF01304 ABF01305 ABF01306 ABF01307 ABF01308 ABF01309 ABF01310 ABF01311 ABF01312 ABF01313 ABF01314 ABF01315 ABF01316 ABF01317 ABF01318 ABF01319 ABF01320 ABF01321 ABF01322 ABF01323 ABF01324 ABF01325 ABF01326 ABF01327 ABF01328 ABF01329 ABF01330 ABF01331 ABF01332 ABF01333 ABF01334 ABF01335 ABF01336 ABF01337 ABF01338 ABF01339 ABF01340 ABF01341 ABF01342 ABF01343 ABF01344 ABF01345 ABF01346 ABF01347 ABF01348 ABF01349 ABF01350 ABF01351 ABF01352 ABF01353 ABF01354 ABF01355 ABF01356 ABF01357 ABF01358 ABF01359 ABF01360 ABF01361 ABF01362 ABF01363 ABF01364 ABF01365 ABF01366 ABF01367 ABF01368 ABF01369 ABF01370 ABF01371 ABF01372 ABF01373 ABF01374 ABF01375 ABF01376 ABF01377 ABF01378 ABF01379 ABF01380 ABF01381 ABF01382 ABF01383 ABF01384 ABF01385 ABF01386 ABF01387 ABF01388 ABF01389 ABF01390 ABF01391 ABF01392 ABF01393 ABF01394 ABF01395 ABF01396 ABF01397 ABF01398 ABF01399 ABF01400 ABF01401 ABF01402 ABF01403 ABF01404 ABF01405 ABF01406 ABF01407 ABF01408 ABF01409 ABF01410 ABF01411 ABF01412 ABF01413 ABF01414 ABF01415 ABF01416 ABF01417 ABF01418 ABF01419 ABF01420 ABF01421 ABF01422 ABF01423 ABF01424 ABF01425 ABF01426 ABF01427 ABF01428 ABF01429 ABF01430 ABF01431 ABF01432 ABF01433 ABF01434 ABF01435 ABF01436 ABF01437 ABF01438 ABF01439 ABF01440 ABF01441 ABF01442 ABF01443 ABF01444 ABF01445 ABF01446 ABF01447 ABF01448 ABF01449 ABF01450 ABF01451 ABF01452 ABF01453 ABF01454 ABF01455 ABF01456 ABF01457 ABF01458 ABF01459 ABF01460 ABF01461 ABF01462 ABF01463 ABF01464 ABF01465 ABF01466 ABF01467 ABF01468 ABF01469 ABF01470 ABF01471 ABF01472 ABF01473 ABF01474 ABF01475 ABF01476 ABF01477 ABF01478 ABF01479 ABF01480 ABF01481 ABF01482 ABF01483 ABF01484 ABF01485 ABF01486 ABF01487 ABF01488 ABF01489 ABF01490 ABF01491 ABF01492 ABF01493 ABF01494 ABF01495 ABF01496 ABF01497 ABF01498 ABF01499 ABF01500 ABF01501 ABF01502 ABF01503 ABF01504 ABF01505 ABF01506 ABF01507 ABF01508 ABF01509 ABF01510 ABF01511 ABF01512 ABF01513 ABF01514 ABF01515 ABF01516 ABF01517 ABF01518 ABF01519 ABF01520 ABF01521 ABF01522 ABF01523 ABF01524 ABF01525 ABF01526 ABF01527 ABF01528 ABF01529 ABF01530 ABF01531 ABF01532 ABF01533 ABF01534 ABF01535 ABF01536 ABF01537 ABF01538 ABF01539 ABF01540 ABF01541 ABF01542 ABF01543 ABF01544 ABF01545 ABF01546 ABF01547 ABF01548 ABF01549 ABF01550 ABF01551 ABF01552 ABF01553 ABF01554 ABF01555 ABF01556 ABF01557 ABF01558 ABF01559 ABF01560 ABF01561 ABF01562 ABF01563 ABF01564 ABF01565 ABF01566 ABF01567 ABF01568 ABF01569 ABF01570 ABF01571 ABF01572 ABF01573 ABF01574 ABF01575 ABF01576 ABF01577 ABF01578 ABF01579 ABF01580 ABF01581 ABF01582 ABF01583 ABF01584 ABF01585 ABF01586 ABF01587 ABF01588 ABF01589 ABF01590 ABF01591 ABF01592 ABF01593 ABF01594 ABF01595 ABF01596 ABF01597 ABF01598 ABF01599 ABF01600 ABF01601 ABF01602 ABF01603 ABF01604 ABF01605 ABF01606 ABF01607 ABF01608 ABF01609 ABF01610 ABF01611 ABF01612 ABF01613 ABF01614 ABF01615 ABF01616 ABF01617 ABF01618 ABF01619 ABF01620 ABF01621 ABF01622 ABF01623 ABF01624 ABF01625 ABF01626 ABF01627 ABF01628 ABF01629 ABF01630 ABF01631 ABF01632 ABF01633 ABF01634 ABF01635 ABF01636 ABF01637 ABF01638 ABF01639 ABF01640 ABF01641 ABF01642 ABF01643 ABF01644 ABF01645 ABF01646 ABF01647 ABF01648 ABF01649 ABF01650 ABF01651 ABF01652 ABF01653 ABF01654 ABF01655 ABF01656 ABF01657 ABF01658 ABF01659 ABF01660 ABF01661 ABF01662 ABF01663 ABF01664 ABF01665 ABF51604 ABF57555 ABF57556 ABF57557 ABF57558 ABK34557 ABK34558 ABK34559 ABK34560 ABK34561 ABK34562 ABK34563 ABK34564 ABK34565 ABK34566 ABK34567 ABK34568 ABK34569 ABK34570 ABK34571 ABK34572 ABK34573 ABK34574 ABK34575 ABK34576 ABK34577 ABK34578 ABK34579 ABK34580 ABK34581 ABK34582 ABK34583 ABK34584 ABK34585 ABK34586 ABK34587 ABK34588 ABK34589 ABK34590 ABK34591 ABK34592 ABK34593 ABK34594 ABK34595 ABK34596 ABK34597 ABK34598 ABK34599 ABK34600 ABK34601 ABK34602 ABK34603 ABK34604 ABK34605 ABK34606 ABK34607 ABK34608 ABK34609 ABK34610 ABK34611 ABK34612 ABK34613 ABK34614 ABK34615 ABK34616 ABK34617 ABK34618 ABK34619 ABK34620 ABK34621 ABK34622 ABK34623 ABK34624 ABK34625 ABK34626 ABK34627 ABK34628 ABK34629 ABK34630 ABK34631 ABK34632 ABK34633 ABK34634 ABK34635 ABK34636 ABK34637 ABK34638 ABK34639 ABK34640 ABK34641 ABK34642 ABK34643 ABK34644 ABK34645 ABK34646 ABK34647 ABK34648 ABK34649 ABK34650 ABK34651 ABK34652 ABK34653 ABK34654 ABK34655 ABK34656 ABK34657 ABK34658 ABK34659 ABK34660 ABK34661 ABK34662 ABK34663 ABK34664 ABK34665 ABK34666 ABK34667 ABK34668 ABK34669 ABK34670 ABK34671 ABK34672 ABK34673 ABK34674 ABK34675 ABK34676 ABK34677 ABK34678 ABK34679 ABK34680 ABK34681 ABK34682 ABK34683 ABK34684 ABK34685 ABK34686 ABK34687 ABK34688 ABK34689 ABK34690 ABK34691 ABK34692 ABK34693 ABK34694 ABK34695 ABK34696 ABK34697 ABK34698 ABK34699 ABK34700 ABK34701 ABK34702 ABK34703 ABK34704 ABK34705 ABK34706 ABK34707 ABK34708 ABK34709 ABK34710 ABK34711 ABK34712 ABK34713 ABK34714 ABK34715 ABK34716 ABK34717 ABK34718 ABK34719 ABK34720 ABK34721 ABK34722 ABK34723 ABK34724 ABK34725 ABK34726 ABK34727 ABK34728 ABK34729 ABK34730 ABK34731 ABK34732 ABK34733 ABK34734 ABK34735 ABK34736 ABK34737 ABK34738 ABK34739 ABK34740 ABK34741 ABK34742 ABK34743 ABK34744 ABK34745 ABK34746 ABK34747 ABK34748 ABK34749 ABK34750 BAA01640 BAA01641 BAA01642 CAA32802 EAW63785 EAW63786 P11245 AI460128 AJ581144 CAE46171 AJ581145 CAE46172 AJ581146 CAE46173 AJ581147 CAE46174 BC015878 AAH15878 BC067218 AAH67218 CR407631 CAG28559 D90040 BAA14094 D90042 BAA14096 XM_011544358 XP_011542660 NM_000015 NP_000006 |
| Function | Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Chemical carcinogenesis, Caffeine metabolism, Drug metabolism - other enzymes |