Grm6

Gene Symbol	Grm6
Entrez Gene	24419
Alt Symbol	mGluR6
Species	Rat
Gene Type	protein-coding
Description	glutamate receptor, metabotropic 6
Other Description	metabotropic glutamate receptor 6
Swissprots	P35349
Accessions	EDM04284 P35349 AJ245718 CAC00714 D13963 BAA03066 XM_006246225 XP_006246287 XR_594657 NM_022920 NP_075209
Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision. {ECO:0000250, ECO:0000269|PubMed:8389366}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Note=Subject to trafficking from the endoplasmic reticulum to the Golgi apparatus and then to the cell membrane. Detected at dendritic tips of bipolar cells (By similarity). {ECO:0000250}.
Tissue Specificity	Restricted expression in the inner nuclear layer of the retina. {ECO:0000269|PubMed:8389366}.
Top Pathways	Glutamatergic synapse, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Anti-Metabotropic Glutamate Receptor 6 antibody - ab10314 from Abcam Prices $370.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

mGluR6 Antibody - NB300-189 from Novus Biologicals Prices $99.00, $329.00 Sizes 25 µl, 100 µl Host Rabbit Clonality Polyclonal

mGluR6 Antibody [DyLight 650] - NB300-189C from Novus Biologicals Prices $319.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

mGluR6 Antibody [Biotin] - NB300-189B from Novus Biologicals Prices $299.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

mGluR6 Antibody [DyLight 488] - NB300-189G from Novus Biologicals Prices $319.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

mGluR6 Antibody [HRP] - NB300-189H from Novus Biologicals Prices $319.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

mGluR6 Antibody [DyLight 550] - NB300-189R from Novus Biologicals Prices $319.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

mGluR6 Antibody [Alexa Fluor (R) 700] - NB300-189AF700 from Novus Biologicals Prices $319.00 Sizes 100 tests Host Rabbit Clonality Polyclonal

mGluR6 Antibody [Alexa Fluor (R) 647] - NB300-189AF647 from Novus Biologicals Prices $319.00 Sizes 100 tests Host Rabbit Clonality Polyclonal

mGluR6 Antibody [Alexa Fluor (R) 488] - NB300-189AF488 from Novus Biologicals Prices $329.00 Sizes 100 tests Host Rabbit Clonality Polyclonal

mGluR6 Antibody [Alexa Fluor (R) 405] - NB300-189AF405 from Novus Biologicals Prices $319.00 Sizes 100 tests Host Rabbit Clonality Polyclonal

mGluR6-extracellular-Antibody - AG1248 from Abgent, a WuXi AppTec company Prices $375.00, $475.00, $575.00 Sizes 25 µl, 50 µl, 200 µl Host Rabbit Clonality Polyclonal

mGluR6 antibody - GTX30457 from GeneTex Prices $339.00 Sizes 100 μl Host Rabbit Clonality Polyclonal

mGluR6 / GRM6 antibody - PAB12109 from Acris Antibodies Prices $500.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-GRM6 polyclonal antibody - DPAB2749RR from Creative Diagnostics Host Rabbit Clonality Polyclonal

mGluR6 Polyclonal Antibody - PA1-32350 from Thermo Fisher Scientific Prices $425.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

mGluR 6 Antibody - PA1-46253 from Thermo Fisher Scientific Prices $354.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

mGluR6 / GRM6 antibody - TA328841 from Acris Antibodies Prices $435.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Search more