| Gene Symbol |
ACSF3
|
| Entrez Gene |
197322
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
acyl-CoA synthetase family member 3
|
| Other Description |
acyl-CoA synthetase family member 3, mitochondrial|malonyl-CoA synthetase
|
| Swissprots |
C9JQL6 Q4G176 Q8N2F7 Q6INA0 A8K4J8
|
| Accessions |
CAI72159 CBX47443 EAW66744 Q4G176 AK075499 BAC11654 AK096561 AK290963 BAF83652 BC028399 AAH28399 BC064609 AAH64609 BC072391 AAH72391 BI837487 BM148793 BQ953430 BX325026 BX402632 BX404035 CR976321 DA062861 HY100877 XM_005256293 XP_005256350 XM_011522942 XP_011521244 XM_011522943 XP_011521245 XM_011522944 XP_011521246 XR_933238 XR_933239 XR_933240 XR_933241 NM_001127214 NP_001120686 NM_001243279 NP_001230208 NM_001284316 NP_001271245 NM_174917 NP_777577 NR_045667 NR_104293 NR_045666
|
| Function |
Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates. {ECO:0000269|PubMed:17762044, ECO:0000269|PubMed:21841779}.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:21841779}.
|
| Top Pathways |
Valine, leucine and isoleucine degradation
|