| Gene Symbol |
ALG1
|
| Entrez Gene |
56052
|
| Alt Symbol |
CDG1K, HMAT1, HMT-1, HMT1, MT-1, Mat-1, hMat-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
|
| Other Description |
GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase|GDP-mannose-dolichol diphosphochitobiose mannosyltransferase|asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase)|asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog|asparagine-linked glycosylation protein 1 homolog|beta-1,4 mannosyltransferase|beta-1,4-mannosyltransferase|chitobiosyldiphosphodolichol beta-mannosyltransferase|mannosyltransferase-1
|
| Swissprots |
Q9P2Y2 Q6UVZ9 Q8N5Y4 Q9BT22 B4DP08
|
| Accessions |
CAI72079 EAW85240 EAW85241 Q9BT22 AA810665 AB019038 BAA90748 AK075373 BAC11576 AK298144 BAG60420 AK311475 AY359073 AAQ89432 BC004402 AAH04402 BC031095 AAH31095 BC031873 BM767933 BQ002699 CA455103 CD366777 DA879477 DQ895010 ABM85936 EU176309 ABW03760 XM_011522565 XP_011520867 XR_932882 NM_019109 NP_061982
|
| Function |
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER. {ECO:0000269|PubMed:10704531}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Top Pathways |
N-Glycan biosynthesis
|
![Western Blot: ALG1 Overexpression Lysate [H00056052-T01] - Lane 1: ALG1 transfected lysate (51.15 KDa) Lane 2: Non-transfected lysate.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/26802_ALG1%2520Overexpression%2520Lysate-Western%2520Blot-H00056052-T01-img0002.jpg)