Gene Symbol | ALG1 |
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Entrez Gene | 56052 |
Alt Symbol | CDG1K, HMAT1, HMT-1, HMT1, MT-1, Mat-1, hMat-1 |
Species | Human |
Gene Type | protein-coding |
Description | ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase |
Other Description | GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase|GDP-mannose-dolichol diphosphochitobiose mannosyltransferase|asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase)|asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog|asparagine-linked glycosylation protein 1 homolog|beta-1,4 mannosyltransferase|beta-1,4-mannosyltransferase|chitobiosyldiphosphodolichol beta-mannosyltransferase|mannosyltransferase-1 |
Swissprots | Q9P2Y2 Q6UVZ9 Q8N5Y4 Q9BT22 B4DP08 |
Accessions | CAI72079 EAW85240 EAW85241 Q9BT22 AA810665 AB019038 BAA90748 AK075373 BAC11576 AK298144 BAG60420 AK311475 AY359073 AAQ89432 BC004402 AAH04402 BC031095 AAH31095 BC031873 BM767933 BQ002699 CA455103 CD366777 DA879477 DQ895010 ABM85936 EU176309 ABW03760 XM_011522565 XP_011520867 XR_932882 NM_019109 NP_061982 |
Function | Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER. {ECO:0000269|PubMed:10704531}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Top Pathways | N-Glycan biosynthesis |
ALG1 CRISPR/Cas9 KO Plasmid (h) - sc-408261 from Santa Cruz Biotechnology
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ALG1 HDR Plasmid (h) - sc-408261-HDR from Santa Cruz Biotechnology
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ALG1 Double Nickase Plasmid (h) - sc-408261-NIC from Santa Cruz Biotechnology
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ALG1 Double Nickase Plasmid (h2) - sc-408261-NIC-2 from Santa Cruz Biotechnology
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ALG1 CRISPR Activation Plasmid (h) - sc-408261-ACT from Santa Cruz Biotechnology
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ALG1 CRISPR Activation Plasmid (h2) - sc-408261-ACT-2 from Santa Cruz Biotechnology
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ALG1 Lentiviral Activation Particles (h) - sc-408261-LAC from Santa Cruz Biotechnology
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ALG1 Lentiviral Activation Particles (h2) - sc-408261-LAC-2 from Santa Cruz Biotechnology
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ALG1 siRNA (h) - sc-93109 from Santa Cruz Biotechnology
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ALG1 shRNA Plasmid (h) - sc-93109-SH from Santa Cruz Biotechnology
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ALG1 shRNA (h) Lentiviral Particles - sc-93109-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU146901 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3051 from Sigma-Aldrich
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ALG1 siRNA (Human) - CRJ1043 from Cohesion Biosciences
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ALG1 RNAi - H00056052-R01 from Novus Biologicals
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ALG1 - MBS8233862 from MyBioSource
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Human ALG1 siRNA - orb271544 from Biorbyt
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ALG1 shRNA Plasmid (Human) - CHJ1043 from Cohesion Biosciences
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