| Gene Symbol |
PROC
|
| Entrez Gene |
5624
|
| Alt Symbol |
APC, PC, PROC1, THPH3, THPH4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein C (inactivator of coagulation factors Va and VIIIa)
|
| Other Description |
anticoagulant protein C|autoprothrombin IIA|blood coagulation factor XIV|prepro-protein C|vitamin K-dependent protein C
|
| Swissprots |
Q53S74 Q15189 B4DPQ7 Q9UC55 Q15190 Q16001 P04070
|
| Accessions |
AAA60165 AAA60166 AAB25410 AAB26335 AAK56377 AAQ24849 AAQ24850 AAR23427 AAY15044 AFO53522 BAC21165 BAC21166 BAC21167 BAC21168 BAC21169 BAC21170 BAC21171 BAC21172 BAC53629 BAC53630 BAC53631 BAC54280 CAF32600 CAG34344 CAL24228 CAX30697 CAX30698 EAW95320 P04070 AK298280 BAG60540 AK298449 BAG60665 AK298454 BAG60669 AK303773 BAG64736 BC034377 AAH34377 BM975043 CB113383 DA642156 DQ890791 ABM81717 DQ893947 ABM84873 K02059 AAA60164 S50739 AAB24150 S72338 AAB31410 X02750 CAA26528 XM_005263715 XP_005263772 XM_005263716 XP_005263773 XM_005263717 XP_005263774 NM_000312 NP_000303
|
| Function |
Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.
|
| Tissue Specificity |
Plasma; synthesized in the liver.
|
| Top Pathways |
Complement and coagulation cascades
|
