GAD1
| Gene Symbol | GAD1 |
|---|---|
| Entrez Gene | 2571 |
| Alt Symbol | CPSQ1, GAD, SCP |
| Species | Human |
| Gene Type | protein-coding |
| Description | glutamate decarboxylase 1 (brain, 67kDa) |
| Other Description | 67 kDa glutamic acid decarboxylase|GAD-67|glutamate decarboxylase 1|glutamate decarboxylase 67 kDa isoform |
| Swissprots | Q53TQ7 Q49AK1 Q99259 Q9BU91 Q9UHH4 |
| Accessions | AAA35900 AAP88035 AAY24237 ABI49508 EAX11228 EAX11229 EAX11230 Q99259 A28074 CAA01913 AF178853 AAF18390 AK127781 AK292582 BAF85271 AK307460 BC002815 AAH02815 BC026349 AAH26349 BC036552 AAH36552 BC037780 AAH37780 DQ892376 ABM83302 DQ895590 ABM86516 L16888 AAB59427 M55574 AAA72938 M70434 AAA52512 M81883 AAA62368 S61897 AAB26937 S61898 AAB26938 Z22750 CAA80435 XM_005246444 XP_005246501 XM_011510922 XP_011509224 NM_000817 NP_000808 NM_013445 NP_038473 |
| Function | Catalyzes the production of GABA. |
| Tissue Specificity | Isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. {ECO:0000269|PubMed:10671565}. |
| Top Pathways | Type I diabetes mellitus, GABAergic synapse, Taurine and hypotaurine metabolism, Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism |
GAD-67 CRISPR/Cas9 KO Plasmid (h) - sc-400588 from Santa Cruz Biotechnology
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GAD-67 HDR Plasmid (h) - sc-400588-HDR from Santa Cruz Biotechnology
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GAD-67 Double Nickase Plasmid (h) - sc-400588-NIC from Santa Cruz Biotechnology
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GAD-67 Double Nickase Plasmid (h2) - sc-400588-NIC-2 from Santa Cruz Biotechnology
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GAD-67 CRISPR Activation Plasmid (h) - sc-400588-ACT from Santa Cruz Biotechnology
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GAD-67 CRISPR Activation Plasmid (h2) - sc-400588-ACT-2 from Santa Cruz Biotechnology
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GAD-67 Lentiviral Activation Particles (h) - sc-400588-LAC from Santa Cruz Biotechnology
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GAD-67 Lentiviral Activation Particles (h2) - sc-400588-LAC-2 from Santa Cruz Biotechnology
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GAD-67 siRNA (h) - sc-35435 from Santa Cruz Biotechnology
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GAD-67 shRNA Plasmid (h) - sc-35435-SH from Santa Cruz Biotechnology
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GAD-67 shRNA (h) Lentiviral Particles - sc-35435-V from Santa Cruz Biotechnology
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GAD-25/67 siRNA (h) - sc-43790 from Santa Cruz Biotechnology
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GAD-25/67 shRNA Plasmid (h) - sc-43790-SH from Santa Cruz Biotechnology
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GAD-25/67 shRNA (h) Lentiviral Particles - sc-43790-V from Santa Cruz Biotechnology
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GAD1/GAD67 RNAi - H00002571-R02 from Novus Biologicals
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GAD1/GAD67 RNAi - H00002571-R01 from Novus Biologicals
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MISSION® esiRNA - EHU085621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1823 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1823 from Sigma-Aldrich
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GAD1 siRNA (Human) - CRH1709 from Cohesion Biosciences
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GAD1 - MBS828868 from MyBioSource
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shRNA set against Human GAD1 (NM_000817.2) - SHH298665 from Creative biogene
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shRNA set against Human GAD1(NM_000817.2) - SHH074837 from Creative biogene
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shRNA set against Human GAD1(NM_013445.3) - SHH074891 from Creative biogene
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Human GAD1 siRNA - orb262211 from Biorbyt
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