Gene Symbol | BEX1 |
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Entrez Gene | 55859 |
Alt Symbol | BEX2, HBEX2, HGR74-h |
Species | Human |
Gene Type | protein-coding |
Description | brain expressed, X-linked 1 |
Other Description | brain-expressed X-linked protein 1|ovarian granulosa cell 13.0 kDa protein hGR74|protein BEX1 |
Swissprots | A8K4J3 A0AVN1 Q9HBH7 Q9NZ33 |
Accessions | EAW54723 Q9HBH7 AF183416 AAG09685 AF220189 AAF67654 AF237783 AAG09752 AK290958 BAF83647 AY833561 AAX40679 BC018615 BC105298 BC126427 AAI26428 BC126429 AAI26430 BM465948 BX098763 HQ258716 ADR83467 NM_018476 NP_060946 |
Function | Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. {ECO:0000250}. |
Tissue Specificity | Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia. {ECO:0000269|PubMed:11989783, ECO:0000269|PubMed:15920485, ECO:0000269|PubMed:15958283}. |
Bex1 (N-14) - sc-48963 from Santa Cruz Biotechnology
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Bex1/2 (D-6) - sc-376342 from Santa Cruz Biotechnology
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Bex1/2 (C-12) - sc-48964 from Santa Cruz Biotechnology
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Bex1/2 (E-12) - sc-48965 from Santa Cruz Biotechnology
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Bex1/2 (H-72) - sc-98914 from Santa Cruz Biotechnology
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Anti-Bex1 antibody - ab68936 from Abcam
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Anti-Bex1 antibody - ab69032 from Abcam
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Anti-Bex1 antibody - ab41807 from Abcam
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Anti-Bex1 antibody - ab107215 from Abcam
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Anti-BEX1 Antibody (aa50-150) - LS-C74800 from LifeSpan Bioscience
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Anti-BEX1 Antibody (aa63-90, APC) - LS-C246960 from LifeSpan Bioscience
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Anti-BEX1 Antibody (aa63-90, PE) - LS-C233139 from LifeSpan Bioscience
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Anti-BEX1 Antibody (aa63-90, FITC) - LS-C233138 from LifeSpan Bioscience
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Anti-BEX1 Antibody (aa63-90, AP) - LS-C246956 from LifeSpan Bioscience
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Anti-BEX1 Antibody (aa63-90, Biotin) - LS-C246962 from LifeSpan Bioscience
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Anti-BEX1 Antibody (aa66-94) - LS-C319834 from LifeSpan Bioscience
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Anti-BEX1 Antibody (aa63-90, Azide-free, HRP) - LS-C249522 from LifeSpan Bioscience
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Anti-BEX1 Antibody (clone 9E1237.1) - LS-C532 from LifeSpan Bioscience
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Anti-BEX1 Antibody (aa63-90) - LS-C156802 from LifeSpan Bioscience
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Bex1 Antibody (9E1237.1) - NB100-56591 from Novus Biologicals
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Bex1 Antibody (9E1237.1) [Alexa Fluor (R) 700] - NB100-56591AF700 from Novus Biologicals
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Bex1 Antibody (9E1237.1) [Alexa Fluor (R) 647] - NB100-56591AF647 from Novus Biologicals
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Bex1 Antibody (9E1237.1) [Alexa Fluor (R) 488] - NB100-56591AF488 from Novus Biologicals
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Bex1 Antibody (9E1237.1) [Alexa Fluor (R) 405] - NB100-56591AF405 from Novus Biologicals
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Bex1 Antibody (9E1237.1) [Azide Free] - NBP2-33234 from Novus Biologicals
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