BEX1

Gene Symbol BEX1
Entrez Gene 55859
Alt Symbol BEX2, HBEX2, HGR74-h
Species Human
Gene Type protein-coding
Description brain expressed, X-linked 1
Other Description brain-expressed X-linked protein 1|ovarian granulosa cell 13.0 kDa protein hGR74|protein BEX1
Swissprots A8K4J3 A0AVN1 Q9HBH7 Q9NZ33
Accessions EAW54723 Q9HBH7 AF183416 AAG09685 AF220189 AAF67654 AF237783 AAG09752 AK290958 BAF83647 AY833561 AAX40679 BC018615 BC105298 BC126427 AAI26428 BC126429 AAI26430 BM465948 BX098763 HQ258716 ADR83467 NM_018476 NP_060946
Function Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity). {ECO:0000250}.
Subcellular Location Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. {ECO:0000250}.
Tissue Specificity Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia. {ECO:0000269|PubMed:11989783, ECO:0000269|PubMed:15920485, ECO:0000269|PubMed:15958283}.

Bex1 (N-14) - sc-48963 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Bex1/2 (D-6) - sc-376342 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Bex1/2 (D-6): sc-376342. Western blot analysis of Bex2 expression in non-transfected: sc-110760 (A) and human Bex2 transfected: sc-113220 (B) 293 whole cell lysates.

Bex1/2 (C-12) - sc-48964 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Bex1/2 (E-12) - sc-48965 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Bex1/2 (H-72) - sc-98914 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-Bex1 antibody - ab68936 from Abcam

Host Rabbit
Clonality Polyclonal
ICC/IF image of ab68936 stained U87-MG cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab68936 at 1/1000 dilution overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Bex1 antibody - ab69032 from Abcam

Host Rabbit
Clonality Polyclonal
ab69032 at a 1/200 dilution staining Bex1 in human whole blood by Immunocytochemistry/ Immunofluorescence (cytospin preparation).

Anti-Bex1 antibody - ab41807 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bex1 antibody (ab41807) at 1 µg/mlLane 1 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell Lysate Lane 2 : SK N BE (Human neuroblastoma) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Bex1 antibody - ab107215 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Bex1 antibody (ab107215) at 1/100 dilution + WiDr cell line lysates at 35 µg

Anti-BEX1 Antibody (aa50-150) - LS-C74800 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-BEX1 Antibody (aa63-90, APC) - LS-C246960 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BEX1 Antibody (aa63-90, PE) - LS-C233139 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BEX1 Antibody (aa63-90, FITC) - LS-C233138 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BEX1 Antibody (aa63-90, AP) - LS-C246956 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BEX1 Antibody (aa63-90, Biotin) - LS-C246962 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BEX1 Antibody (aa66-94) - LS-C319834 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BEX1 Antibody (aa63-90, Azide-free, HRP) - LS-C249522 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BEX1 Antibody (clone 9E1237.1) - LS-C532 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 9E1237.1
Western blot of BEX in recombinant-fusion protein using LS-C532 at 2 ug/ml.

Anti-BEX1 Antibody (aa63-90) - LS-C156802 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BEX1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Bex1 Antibody (9E1237.1) - NB100-56591 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 9E1237.1
Western Blot: Bex1 Antibody (9E1237.1) [NB100-56591] - Analysis of BEX in recombinant-fusion protein using BEX monoclonal antibody at 2 ug/ml.  Goat anti-mouse Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Bex1 Antibody (9E1237.1) [Alexa Fluor (R) 700] - NB100-56591AF700 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 9E1237.1

Bex1 Antibody (9E1237.1) [Alexa Fluor (R) 647] - NB100-56591AF647 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 9E1237.1

Bex1 Antibody (9E1237.1) [Alexa Fluor (R) 488] - NB100-56591AF488 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 9E1237.1

Bex1 Antibody (9E1237.1) [Alexa Fluor (R) 405] - NB100-56591AF405 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 9E1237.1

Bex1 Antibody (9E1237.1) [Azide Free] - NBP2-33234 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 9E1237.1
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