ATP2B4

Gene Symbol ATP2B4
Entrez Gene 493
Alt Symbol ATP2B2, MXRA1, PMCA4, PMCA4b, PMCA4x
Species Human
Gene Type protein-coding
Description ATPase, Ca++ transporting, plasma membrane 4
Other Description matrix-remodeling-associated protein 1|plasma membrane calcium-transporting ATPase 4|sarcolemmal calcium pump
Swissprots Q16817 Q13455 B1APW5 B1APW6 Q13450 Q7Z3S1 Q13452 P23634
Accessions EAW91483 EAW91484 EAW91485 EAW91486 EAW91487 P23634 AK026443 AK292458 BAF85147 AK307104 AL601702 AL706212 AM393326 CAL38204 AM393354 CAL38232 AW888226 BC062445 BC140774 AAI40775 BC150293 AAI50294 BF740130 BF985985 BX537444 CAD97686 BX537745 BX647701 CR749393 CAH18241 CR936708 DN997129 DQ201780 ABG24244 DQ201781 ABG24245 M25874 AAA50819 M83363 AAA36455 U42026 AAB17577 U42061 AAB17578 U42062 AAB17579 U42378 AAB17580 NM_001001396 NP_001001396 NM_001684 NP_001675
Function This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Isoform XB is the most abundant isoform and is expressed ubiquitously. Isoforms containing segment Z have only been detected in heart, while isoforms containing segment a have been found in heart, stomach and brain cortex.
Top Pathways Calcium signaling pathway, Salivary secretion, Pancreatic secretion, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway

PMCA1/4 (5F10) - sc-20028 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PMCA1/4 (5F10): sc-20028. Western blot analysis of PMCA1/4 expression in JAR (A) and Hep G2 (B) whole cell lysates.

PMCA4 (F-20) - sc-22078 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PMCA4 (F-20): sc-22078. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pre-menopausal uterus tissue showing membrane and cytoplasmic staining of glandular cells.

PMCA4 (H-40) - sc-367142 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

PMCA4 (T-20) - sc-22079 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PMCA1/4 (6D131) - sc-71907 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PMCA1/4 (6D131): sc-71907. Western blot analysis of PMCA1/4 expression in HeLa whole cell lysate.

PMCA4b (JA3) - sc-20027 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PMCA4b (JA3): sc-20027. Western blot analysis of PMCA4b expression in Caki-1 (A), JAR (B), Hep G2 (C) and HeLa (D) whole cell lysates.

PMCA4b (2T2) - sc-71909 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PMCA4b (2T2): sc-71909. Western blot analysis of PMCA4b expression in Hep G2 (A) and HeLa (B) whole cell lysates.

PMCA4b (3F18) - sc-71908 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PMCA4b (3F18): sc-71908. Western blot analysis of PMCA4b expression in Hep G2 (A) and HeLa (B) whole cell lysates.

Anti-ATP2B4 / PMCA4 Antibody (aa51-75) - LS-C74390 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ATP2B4 / PMCA4 Antibody (aa1173-1202, AP) - LS-C212837 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP2B4 / PMCA4 Antibody (aa1173-1202, Biotin) - LS-C212839 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP2B4 / PMCA4 Antibody (clone 2C7) - LS-C196716 from LifeSpan Bioscience

Prices $355.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 2C7

Anti-ATP2B4 / PMCA4 Antibody (aa1173-1202, APC) - LS-C212838 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP2B4 / PMCA4 Antibody (aa1173-1202, FITC) - LS-C212840 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP2B4 / PMCA4 Antibody (aa1173-1202, Azide-free, HRP) - LS-C212841 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP2B4 / PMCA4 Antibody (aa1173-1202, PE) - LS-C212842 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP2B4 / PMCA4 Antibody (aa1173-1202) - LS-C319684 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP2B4 / PMCA4 Antibody (aa936-985) - LS-C102097 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ATP2B4 / PMCA4 antibody LS-C102097 Western blot of 721_B cell lysate.

Anti-ATP2B4 / PMCA4 Antibody (aa1173-1202) - LS-C156650 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ATP2B4 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The ATP2B4 antibody detected the ATP2B4 protein (arrow).

PMCA4 Antibody (JA9) - NB300-569 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone JA9
Immunocytochemistry/Immunofluorescence: PMCA4 Antibody (JA9) [NB300-569] - Immunolocalization of (A) PMCA4 (green), (B) CaSRO (red), and (C) Merged image.

PMCA4 Antibody - NBP2-31984 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PMCA4 Antibody [NBP2-31984] - Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.

PMCA4 Antibody - NBP1-59481 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PMCA4 Antibody [NBP1-59481] - 721_B cell lysate, concentration 0.2-1 ug/ml.

PMCA4 Antibody (2G8) - H00000493-M07 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G8
Sandwich ELISA: PMCA4 Antibody (2G8) [H00000493-M07] - Detection limit for recombinant GST tagged ATP2B4 is 1 ng/ml as a capture antibody.

PMCA4 Antibody (2C7) - H00000493-M03A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 2C7

PMCA4 Antibody - H00000493-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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