Gene Symbol | PBXIP1 |
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Entrez Gene | 57326 |
Alt Symbol | HPIP |
Species | Human |
Gene Type | protein-coding |
Description | pre-B-cell leukemia homeobox interacting protein 1 |
Other Description | hematopoietic PBX-interacting protein|pre-B-cell leukemia transcription factor interacting protein 1|pre-B-cell leukemia transcription factor-interacting protein 1 |
Swissprots | Q9HD85 Q5T176 Q5T174 Q96AQ6 Q9HA02 Q9H8X6 |
Accessions | EAW53174 EAW53175 EAW53176 Q96AQ6 AF221521 AAG02026 AK022497 BAB14059 AK023219 BAB14471 AK300544 BAG62252 AK300987 BAG62606 AK303413 BAG64466 AK303863 BAG64802 AK310388 AK310712 AK315551 BC016852 AAH16852 EU446600 ABZ92129 U00952 NM_020524 NP_065385 |
Function | Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling. {ECO:0000269|PubMed:10825160, ECO:0000269|PubMed:12360403, ECO:0000269|PubMed:17043237}. |
Subcellular Location | Cytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol. Mainly localized in the cytoplasm, associated with microtubules. Detected in small amounts in the nucleus. |
Tissue Specificity | Expressed in early hematopoietic precursors. {ECO:0000269|PubMed:10825160}. |
Anti-PBXIP1 antibody - ab80504 from Abcam
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Anti-PBXIP1 antibody - ab84752 from Abcam
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Anti-PBXIP1 antibody - N-terminal - ab176591 from Abcam
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Anti-PBXIP1 / HPIP Antibody (aa472-501, Biotin) - LS-C238714 from LifeSpan Bioscience
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Anti-PBXIP1 / HPIP Antibody (aa472-501, AP) - LS-C238713 from LifeSpan Bioscience
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Anti-PBXIP1 / HPIP Antibody (aa472-501, APC) - LS-C238712 from LifeSpan Bioscience
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Anti-PBXIP1 / HPIP Antibody (aa472-501, PE) - LS-C238718 from LifeSpan Bioscience
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Anti-PBXIP1 / HPIP Antibody (aa472-501, FITC) - LS-C238715 from LifeSpan Bioscience
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Anti-PBXIP1 / HPIP Antibody (aa472-501, Azide-free, HRP) - LS-C248408 from LifeSpan Bioscience
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Anti-PBXIP1 / HPIP Antibody (aa500-550) - LS-C288420 from LifeSpan Bioscience
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Anti-PBXIP1 / HPIP Antibody (aa471-501) - LS-C323819 from LifeSpan Bioscience
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Anti-PBXIP1 / HPIP Antibody (aa182-231) - LS-C80033 from LifeSpan Bioscience
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Anti-PBXIP1 / HPIP Antibody (aa1-50) - LS-C288416 from LifeSpan Bioscience
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Anti-PBXIP1 / HPIP Antibody (aa472-501) - LS-C163401 from LifeSpan Bioscience
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Anti-PBXIP1 / HPIP Antibody (aa1-50) - LS-C285935 from LifeSpan Bioscience
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PBXIP1 Antibody - NB100-81652 from Novus Biologicals
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PBXIP1 Antibody - NBP1-83222 from Novus Biologicals
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PBXIP1 Antibody - H00057326-B01P from Novus Biologicals
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PBXIP1 Antibody - NB100-81653 from Novus Biologicals
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PBXIP1 Antibody (7E1) - H00057326-M02-100ug from Novus Biologicals
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Anti-PBXIP1 antibody produced in rabbit - HPA006949 from Sigma-Aldrich
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Monoclonal Anti-PBXIP1 antibody produced in mouse - SAB1412864 from Sigma-Aldrich
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Anti-PBXIP1 antibody produced in mouse - SAB1407783 from Sigma-Aldrich
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Anti-PBXIP1 antibody produced in rabbit - SAB2101733 from Sigma-Aldrich
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PBXIP1 antibody - N-terminal region (ARP32948_P050) - ARP32948_P050 from Aviva Systems Biology
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