| Gene Symbol |
CD248
|
| Entrez Gene |
57124
|
| Alt Symbol |
CD164L1, TEM1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CD248 molecule, endosialin
|
| Other Description |
2610111G01Rik|CD164 sialomucin-like 1|CD248 antigen, endosialin|endosialin|tumor endothelial marker 1
|
| Swissprots |
Q9HCU0 Q3SX55 Q2M2V5 Q96KB6
|
| Accessions |
EAW74511 Q9HCU0 AF279142 AAG00867 AJ295846 CAC34381 AK027290 BAB55018 BC051340 AAH51340 BC098158 BC104484 AAI04485 BC105633 AAI05634 BQ005949 NM_020404 NP_065137
|
| Function |
May play a role in tumor angiogenesis. {ECO:0000269|PubMed:15862292}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts. {ECO:0000269|PubMed:10947988, ECO:0000269|PubMed:11084048, ECO:0000269|PubMed:1438285, ECO:0000269|PubMed:15862292, ECO:0000269|PubMed:16076089}.
|
![Western Blot: TEM1 Overexpression Lysate (Adult Normal) [NBP2-06637] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TEM1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/16568_TEM1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-06637-img0001.jpg)