Gene Symbol | SRF |
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Entrez Gene | 6722 |
Alt Symbol | MCM1 |
Species | Human |
Gene Type | protein-coding |
Description | serum response factor (c-fos serum response element-binding transcription factor) |
Other Description | serum response factor |
Swissprots | P11831 Q5T648 |
Accessions | CAM91173 EAX04161 EAX04162 P11831 AB209128 BAD92365 AI085561 AK300467 BAG62186 BC048211 AAH48211 BC052572 AAH52572 J03161 AAA36647 NM_001292001 NP_001278930 NM_003131 NP_003122 |
Function | SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentiation and maturation. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00251, ECO:0000269|PubMed:19350017}. |
Top Pathways | MAPK signaling pathway, HTLV-I infection, Viral carcinogenesis, cGMP-PKG signaling pathway |
SRF CRISPR/Cas9 KO Plasmid (h) - sc-400470 from Santa Cruz Biotechnology
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SRF HDR Plasmid (h) - sc-400470-HDR from Santa Cruz Biotechnology
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SRF Double Nickase Plasmid (h) - sc-400470-NIC from Santa Cruz Biotechnology
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SRF Double Nickase Plasmid (h2) - sc-400470-NIC-2 from Santa Cruz Biotechnology
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SRF CRISPR Activation Plasmid (h) - sc-400470-ACT from Santa Cruz Biotechnology
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SRF CRISPR Activation Plasmid (h2) - sc-400470-ACT-2 from Santa Cruz Biotechnology
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SRF Lentiviral Activation Particles (h) - sc-400470-LAC from Santa Cruz Biotechnology
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SRF Lentiviral Activation Particles (h2) - sc-400470-LAC-2 from Santa Cruz Biotechnology
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SRF siRNA (h) - sc-36563 from Santa Cruz Biotechnology
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SRF shRNA Plasmid (h) - sc-36563-SH from Santa Cruz Biotechnology
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SRF shRNA (h) Lentiviral Particles - sc-36563-V from Santa Cruz Biotechnology
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Serum Response Factor SRF RNAi - H00006722-R01 from Novus Biologicals
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MISSION® esiRNA - EHU003471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1541 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1541 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11260 from Sigma-Aldrich
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SRF siRNA (Human) - CRH4590 from Cohesion Biosciences
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SRF - MBS8203027 from MyBioSource
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shRNA set against Human SRF (NM_003131.2) - SHH417776 from Creative biogene
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shRNA set against Human SRF(NM_003131.2) - SHL033156 from Creative biogene
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SRF shRNA Plasmid (Human) - CHH4590 from Cohesion Biosciences
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SRF miRNA 3'UTR clone - MiUTR1H-09900 from Creative biogene
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