Kras

Gene Symbol Kras
Entrez Gene 16653
Alt Symbol AI929937, K-ras, Ki-ras, Kras-2, Kras2, p21B, ras
Species Mouse
Gene Type protein-coding
Description v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Other Description GTPase KRas|K-Ras 2|Kirsten rat sarcoma oncogene 2, expressed|c-K-ras|c-Ki-ras|p21 protein
Swissprots P08643 P04200 P32883
Accessions AAA40037 AAO46052 CAA26295 CAA26296 CAA33897 CDL93478 EDL10686 P32883 AK155064 BAE33023 AK164065 BAE37609 AY487807 AAS58056 BC004642 AAH04642 BC010202 AAH10202 BC014700 BC031623 BC119495 AAI19496 BC141051 AAI41052 U76425 U76426 X00485 CAA25160 XM_006506918 XP_006506981 XM_006506919 XP_006506982 XM_006536039 XP_006536102 XM_006536040 XP_006536103 NM_021284 NP_067259
Function Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation (PubMed:6474169, PubMed:1352876). {ECO:0000250|UniProtKB:P01116, ECO:0000269|PubMed:1352876, ECO:0000269|PubMed:6474169}.
Subcellular Location Cell membrane {ECO:0000250|UniProtKB:P01116}; Lipid-anchor {ECO:0000250|UniProtKB:P01116}; Cytoplasmic side {ECO:0000250|UniProtKB:P01116}. Cytoplasm {ECO:0000250|UniProtKB:P01116}.
Top Pathways Axon guidance, Tight junction, VEGF signaling pathway, Gap junction, Natural killer cell mediated cytotoxicity

Search more