| Gene Symbol |
GC
|
| Entrez Gene |
2638
|
| Alt Symbol |
DBP, DBP/GC, GRD3, HEL-S-51, VDBG, VDBP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
group-specific component (vitamin D binding protein)
|
| Other Description |
VDB|epididymis secretory protein Li 51|gc-globulin|vitamin D-binding alpha-globulin|vitamin D-binding protein
|
| Swissprots |
Q16310 P02774 Q6GTG1 Q53F31 Q16309 D6RAK8 B4DPP2
|
| Accessions |
AAA19662 AAA61704 AAB29423 AAD13872 AAD14249 AAD14250 AJS18493 EAX05645 P02774 AA702473 AK223458 BAD97178 AK290827 BAF83516 AK298433 BAG60654 AK309595 AK312971 AK315853 BAF98744 BC022310 BC057228 AAH57228 BX494962 EU794674 ACJ13728 X03178 CAA26938 XM_006714177 XP_006714240 NM_000583 NP_000574 NM_001204306 NP_001191235 NM_001204307 NP_001191236
|
| Function |
Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
|
| Subcellular Location |
Secreted.
|