| Gene Symbol |
PCGF3
|
| Entrez Gene |
10336
|
| Alt Symbol |
DONG1, RNF3, RNF3A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
polycomb group ring finger 3
|
| Other Description |
RING finger protein 3A|polycomb group RING finger protein 3|ring finger protein 3
|
| Swissprots |
Q3KNV8 O15262 D3DVN1
|
| Accessions |
EAW82651 EAW82652 EAW82653 EAW82654 EAW82655 EAW82656 Q3KNV8 AA401257 AK057124 BAG51868 AK125801 BAG54250 AK225892 AK300290 BAG62047 AL832536 CAD38631 AU132917 BC028026 BC050044 BC061897 BC107061 AAI07062 BI758022 BQ882065 BX640894 BX648409 CA454695 CX761238 CX761943 XM_005272250 XP_005272307 XM_005272253 XP_005272310 XM_005272254 XP_005272311 XM_006713852 XP_006713915 XM_011513381 XP_011511683 XM_011513382 XP_011511684 XM_011513383 XP_011511685 XM_011513384 XP_011511686 XM_011513385 XP_011511687 NM_006315 NP_006306
|
| Function |
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:21282530}.
|
| Top Pathways |
Signaling pathways regulating pluripotency of stem cells
|
![Western Blot: PCGF3 Overexpression Lysate (Adult Normal) [NBP2-07642] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PCGF3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8563_PCGF3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07642-img0001.jpg)