Gene Symbol | REG1A |
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Entrez Gene | 5967 |
Alt Symbol | ICRF, P19, PSP, PSPS, PSPS1, PTP, REG |
Species | Human |
Gene Type | protein-coding |
Description | regenerating islet-derived 1 alpha |
Other Description | REG-1-alpha|islet cells regeneration factor|islet of langerhans regenerating protein|lithostathine 1 alpha|lithostathine-1-alpha|pancreatic stone protein, secretory|pancreatic thread protein|protein-X|regenerating islet-derived protein 1-alpha|regenerating protein I alpha |
Swissprots | P05451 P11379 Q4ZG28 |
Accessions | AAA36559 AAX88842 EAW99576 EAW99577 EAW99578 P05451 AF172331 AAD51330 AK291981 BAF84670 AK307292 AK311087 AW873911 BC005350 AAH05350 BC110438 AAI10439 BC118621 AAI18622 BM769434 M18963 AAA36558 M27190 AAA60546 W38384 NM_002909 NP_002900 |
Function | Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration. |
Subcellular Location | Secreted. |
Tissue Specificity | In pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients. {ECO:0000269|PubMed:2394826}. |
Reg 1α CRISPR/Cas9 KO Plasmid (h) - sc-408024 from Santa Cruz Biotechnology
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Reg 1α HDR Plasmid (h) - sc-408024-HDR from Santa Cruz Biotechnology
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Reg 1α Double Nickase Plasmid (h) - sc-408024-NIC from Santa Cruz Biotechnology
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Reg 1α Double Nickase Plasmid (h2) - sc-408024-NIC-2 from Santa Cruz Biotechnology
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Reg 1α CRISPR Activation Plasmid (h) - sc-408024-ACT from Santa Cruz Biotechnology
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Reg 1α CRISPR Activation Plasmid (h2) - sc-408024-ACT-2 from Santa Cruz Biotechnology
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Reg 1α Lentiviral Activation Particles (h) - sc-408024-LAC from Santa Cruz Biotechnology
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Reg 1α Lentiviral Activation Particles (h2) - sc-408024-LAC-2 from Santa Cruz Biotechnology
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Reg Iα siRNA (h) - sc-76382 from Santa Cruz Biotechnology
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Reg Iα shRNA Plasmid (h) - sc-76382-SH from Santa Cruz Biotechnology
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Reg Iα shRNA (h) Lentiviral Particles - sc-76382-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU106281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18129 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18129 from Sigma-Aldrich
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REG1A siRNA (Human) - CRH4038 from Cohesion Biosciences
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Reg1 RNAi - H00005967-R01 from Novus Biologicals
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REG1A - MBS8200433 from MyBioSource
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shRNA set against Human REG1A (NM_002909.4) - SHH391720 from Creative biogene
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Human REG1A siRNA - orb264540 from Biorbyt
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REG1A shRNA Plasmid (Human) - CHH4038 from Cohesion Biosciences
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REG1A miRNA 3'UTR clone - MiUTR4H-TG07434 from Creative biogene
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