Gene Symbol | ARHGAP22 |
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Entrez Gene | 58504 |
Alt Symbol | RhoGAP2, RhoGap22 |
Species | Human |
Gene Type | protein-coding |
Description | Rho GTPase activating protein 22 |
Other Description | rho GTPase-activating protein 22|rho-type GTPase-activating protein 22 |
Swissprots | C9JDM2 Q7Z5H3 O00152 B9EGA0 B4DED8 A5YM75 Q6ZSB0 A0AVP7 |
Accessions | EAW93125 EAW93126 EAW93127 Q7Z5H3 AK055037 BAG51453 AK055937 AK127586 BAC87044 AK293579 BAG57049 AY324801 AAP85632 BC037890 BC043540 BC047096 BC126444 AAI26445 BC136319 AAI36320 DB338179 DC391765 EF560749 ABQ59059 HG502883 HQ258357 ADR83111 U90908 AAB51057 XM_005270014 XP_005270071 XM_011540002 XP_011538304 XM_011540003 XP_011538305 XM_011540004 XP_011538306 XM_011540005 XP_011538307 XM_011540006 XP_011538308 XM_011540007 XP_011538309 XM_011540008 XP_011538310 XM_011540009 XP_011538311 XM_011540010 XP_011538312 XM_011540011 XP_011538313 XM_011540012 XP_011538314 XM_011540013 XP_011538315 XM_011540014 XP_011538316 XM_011540015 XP_011538317 NM_001256027 NM_001256024 NP_001242953 NM_001256025 NP_001242954 NM_001256026 NP_001242955 NM_021226 NP_067049 NR_045675 |
Function | Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Mainly cytoplasmic. Some fraction is nuclear (By similarity). {ECO:0000250}. |
ARHGAP22 / RhoGAP2 Antibody Blocking Peptide - LS-E2114 from LifeSpan Bioscience
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ARHGAP22 / RhoGAP2 Antibody Blocking Peptide - LS-E24086 from LifeSpan Bioscience
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ARHGAP22-Antibody-C-term-Blocking-peptide - BP13013b from Abgent, a WuXi AppTec company
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ARHGAP22 peptide - orb218605 from Biorbyt
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ARHGAP22 Blocking Peptide - abx063936 from Abbexa
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ARHGAP22 fusion protein - Ag23217 from Proteintech Group
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ARHGAP22 fusion protein - Ag23212 from Proteintech Group
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ARHGAP22 Blocking Peptide - CBP2742 from Cohesion Biosciences
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ARHGAP22 (R595) Peptide - BS3391P from Bioworld Technology
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Recombinant Human Rho GTPase-activating protein 22(ARHGAP22) - CSB-YP773596HU CSB-EP773596HU CSB-BP773596HU CSB-MP773596HU from Cusabio
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ARHGAP22 - TP320614 from Acris Antibodies
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ARHGAP22 (full length, N-term HIS tag) - TP760689 from Acris Antibodies
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ARHGAP22 Recombinant Protein Antigen - NBP2-38465PEP from Novus Biologicals
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ARHGAP22 Recombinant Protein Antigen - NBP2-39028PEP from Novus Biologicals
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ARHGAP22 Peptide, Human - M34GP00852H from Creative Peptides
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Rho GTPase-activating protein 22 (ARHGAP22), Recombinant Protein - MBS1421328 from MyBioSource
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