Gene Symbol | CABP1 |
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Entrez Gene | 9478 |
Alt Symbol | CALBRAIN, HCALB_BR |
Species | Human |
Gene Type | protein-coding |
Description | calcium binding protein 1 |
Other Description | calcium binding protein 5|calcium-binding protein 1|caldendrin |
Swissprots | O95663 Q9NZU8 Q8N6H5 Q9NZU7 |
Accessions | EAW98209 EAW98210 EAW98211 Q9NZU7 AF169148 AAF25782 AF169149 AAF25783 AK127203 AL533429 BC015006 BC030201 AAH30201 BM716422 BQ188859 DQ895513 ABM86439 EU176343 ABW03794 NM_001033677 NP_001028849 NM_004276 NP_004267 NM_031205 NP_112482 |
Function | Modulates calcium-dependent activity of inositol 1,4,5- triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor- induced cellular degeneration (By similarity). {ECO:0000250}. |
Subcellular Location | Isoform S-CaBP1: Cytoplasm, cell cortex. Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Note=S- CaBP1 is localized at or near the plasma membrane. |
Tissue Specificity | Retina and brain. Somatodendritic compartment of neurons. Calbrain was found exclusively in brain where it is abundant in the hippocampus, habenular area in the epithalamus and in the cerebellum. |
Human CABP full length protein - ab131886 from Abcam
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Human CABP peptide - ab108465 from Abcam
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Human CABP peptide - ab22942 from Abcam
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CABP1-Antibody-Center-Blocking-peptide - BP11095c from Abgent, a WuXi AppTec company
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CABP1-Antibody-C-term-Blocking-Peptide - BP7588b from Abgent, a WuXi AppTec company
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CABP1 blocking peptide - GTX89905-PEP from GeneTex
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CABP Peptide - AC21-0236-P from Abcore
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CABP1 - H00009478-P01-10 from Acris Antibodies
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CABP1 - H00009478-P01-25 from Acris Antibodies
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CABP1 Peptide - 45-349P from ProSci
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Recombinant Human Calcium-binding protein 1(CABP1) - CSB-YP868373HU CSB-EP868373HU CSB-BP868373HU CSB-MP868373HU from Cusabio
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CABP1 (transcript variant 1) - TP318317 from Acris Antibodies
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Calcium-binding protein 1 (CABP1), Recombinant Protein - MBS1453446 from MyBioSource
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CABP1, Peptide - MBS425546 from MyBioSource
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