TOP2A

Gene Symbol	TOP2A
Entrez Gene	7153
Alt Symbol	TOP2, TP2A
Species	Human
Gene Type	protein-coding
Description	topoisomerase (DNA) II alpha 170kDa
Other Description	DNA gyrase|DNA topoisomerase (ATP-hydrolyzing)|DNA topoisomerase 2-alpha|DNA topoisomerase II, 170 kD|DNA topoisomerase II, alpha isozyme
Swissprots	Q9HB24 P11388 Q9UQP9 Q9HB25 Q71UQ5 Q71UN1 Q9HB26 B2RTS1 Q9UP44
Accessions	AAC16736 AAC23518 AAC77388 ABA01496 CAA09762 EAW60661 EAW60662 EAW60663 P11388 AF285157 AAG13403 AF285158 AAG13404 AF285159 AAG13405 AK024080 BC013429 BC062677 BC140791 AAI40792 DB069825 J04088 AAA61209 L47276 L47277 XM_005257632 XP_005257689 XM_011525165 XP_011523467 NM_001067 NP_001058
Function	Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity). {ECO:0000250|UniProtKB:Q01320, ECO:0000269|PubMed:18790802, ECO:0000269|PubMed:22013166, ECO:0000269|PubMed:22323612}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:22013166}. Nucleus, nucleoplasm {ECO:0000269|PubMed:22013166}. Note=Generally located in the nucleoplasm.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TOP2A / Topoisomerase II Alpha ELISA Kit (Cell-Based ELISA) - LS-F2360 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-TOP2A / Topoisomerase II Alpha (Ser1525) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1747 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.312-20 ng/ml

Human Phospho-TOP2A / Topoisomerase II Alpha (Thr1343) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1709 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.312-20 ng/ml

Human Phospho-TOP2A / Topoisomerase II Alpha (Ser1106) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1412 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.312-20 ng/ml

Human TOP2A / Topoisomerase II Alpha ELISA Kit (Sandwich ELISA) - LS-F12830 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 ng/ml Range 0.312-20 ng/ml

DNA topoisomerase 2-alpha (TOP2A), Human, ELISA Kit - E01D0310 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

DNA topoisomerase 2-alpha, TOP2A, Human, ELISA Kit - E8718h from ARP American Research Products Category ELISA Kit Prices $660.00 Sizes 96 t Range 0.312-20 ng/mL

Topoisomerase II (TOP2), Human, ELISA Kit - SEA792Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.225ng/mL Range 0.625-40ng/mL

Type II topoisomerase (TopoII), Human, ELISA Kit - CSB-E14049h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

TOP2A Colorimetric Cell-Based ELISA Kit - CB5698 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

TOP2A (Phospho-Ser1106) Colorimetric Cell-Based ELISA Kit - CBP1442 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

TOP2A (Phospho-Thr1343) Colorimetric Cell-Based ELISA Kit - CBP1787 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

TOP2A (Phospho-Ser1525) Colorimetric Cell-Based ELISA Kit - CBP1843 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

DNA topoisomerase 2 Alpha (TOP2A), ELISA Kit - MBS7206606 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA topoisomerase 2-alpha, ELISA Kit - MBS280629 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA topoisomerase 2-alpha (TOP2A), ELISA Kit - MBS7245840 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA topoisomerase 2-alpha (TOP2A), ELISA Kit - MBS7203093 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA topoisomerase 2-alpha (TOP2A), ELISA Kit - MBS7240998 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA topoisomerase 2-alpha (TOP2A), ELISA Kit - MBS7231306 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA topoisomerase 2-alpha (TOP2A), ELISA Kit - MBS7236437 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA topoisomerase 2-alpha (TOP2A), ELISA Kit - MBS7226759 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA topoisomerase 2-alpha (TOP2A), ELISA Kit - MBS7239076 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA topoisomerase 2-alpha (TOP2A), ELISA Kit - MBS7245020 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA topoisomerase 2-alpha (TOP2A), ELISA Kit - MBS7239901 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

DNA topoisomerase 2-alpha (TOP2A), ELISA Kit - MBS7214831 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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