| Gene Symbol |
Pla2g4a
|
| Entrez Gene |
18783
|
| Alt Symbol |
Pla2g4, cPLA2, cPLA2-alpha, cPLA2alpha
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
phospholipase A2, group IVA (cytosolic, calcium-dependent)
|
| Other Description |
Cytosolic phospholipase A2 (CPLA2)|Type IV PLA2|cytosolic PLA2|cytosolic phospholipase A2|phospholipase A2 group IVA|phospholipase A2, group 4
|
| Swissprots |
P47713
|
| Accessions |
EDL39489 P47713 AK004701 BAB23486 AK144750 BAE26047 AK172121 BC003816 AAH03816 BQ033204 M72394 AAB00796 XM_006529252 XP_006529315 NM_001305632 NP_001292561 NM_008869 NP_032895
|
| Function |
Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
|
| Subcellular Location |
Cytoplasm. Cytoplasmic vesicle. Note=Translocates to membrane vesicles in a calcium-dependent fashion.
|
| Top Pathways |
Glutamatergic synapse, Choline metabolism in cancer, Oxytocin signaling pathway, Inflammatory mediator regulation of TRP channels, VEGF signaling pathway
|