Gene Symbol |
ndel1-b
|
Entrez Gene |
447537
|
Alt Symbol |
eopa, mitap1, nudel
|
Species |
Xenopus
|
Gene Type |
protein-coding
|
Description |
nudE neurodevelopment protein 1-like 1
|
Other Description |
nuclear distribution protein nudE-like 1-B|nudE nuclear distribution E homolog-like 1|nudE nuclear distribution gene E homolog-like 1
|
Swissprots |
Q66IZ7
|
Accessions |
Q66IZ7 BC081127 AAH81127 NM_001094244 NP_001087713
|
Function |
Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Localizes to the interphase centrosome and the mitotic spindle. {ECO:0000250}.
|