| Gene Symbol | ARAF |
|---|---|
| Entrez Gene | 369 |
| Alt Symbol | A-RAF, ARAF1, PKS2, RAFA1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | A-Raf proto-oncogene, serine/threonine kinase |
| Other Description | A-Raf proto-oncogene serine/threonine-protein kinase|Oncogene ARAF1|Ras-binding protein DA-Raf|proto-oncogene A-Raf-1|proto-oncogene Pks|serine/threonine-protein kinase A-Raf|v-raf murine sarcoma 3611 viral oncogene homolog 1 |
| Swissprots | Q5H9B2 P07557 Q5H9B3 P10398 |
| Accessions | AAA65219 AAB03517 EAW59310 EAW59311 EAW59312 P10398 AB158254 BAE66645 AB208831 BAD92068 AF052136 AK130043 AK297453 BAG59877 AK300975 BAG62597 AK307747 BC002466 AAH02466 BC007514 AAH07514 BT019864 AAV38667 CA424869 DA264472 DC362427 DQ892656 ABM83582 DQ895896 ABM86822 M13829 AAB08754 X04790 CAA28476 XM_006724529 XP_006724592 XM_011543906 XP_011542208 XM_011543907 XP_011542209 XM_011543908 XP_011542210 XM_011543909 XP_011542211 NM_001256196 NP_001243125 NM_001256197 NP_001243126 NM_001654 NP_001645 |
| Function | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. {ECO:0000269|PubMed:22609986}. |
| Tissue Specificity | Predominantly in urogenital tissues. |
| Top Pathways | Proteoglycans in cancer, Vascular smooth muscle contraction, Hepatitis C, Alcoholism, Natural killer cell mediated cytotoxicity |