| Gene Symbol | PHO4 |
|---|---|
| Entrez Gene | 850594 |
| Alt Symbol | - |
| Species | Yeast |
| Gene Type | protein-coding |
| Description | phosphate-sensing transcription factor PHO4 |
| Other Description | - |
| Swissprots | D6VTR7 P07270 |
| Accessions | DAA12477 P07270 NM_001179999 NP_116692 |
| Function | Transcriptional activator that regulates the expression of repressible phosphatase under phosphate starvation conditions. Binds to the upstream activating sequence (UAS) of several phosphatase encoding PHO genes. Inhibited by the cyclin-CDK PHO80- PHO85 under high-phosphate conditions. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:8539622}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:8539622}. Note=Predominantly cytoplasmic under high-phosphate conditions and localized to the nucleus upon phosphate starvation. |
| Top Pathways | Cell cycle - yeast |