Gene Symbol | EVI5 |
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Entrez Gene | 7813 |
Alt Symbol | NB4S |
Species | Human |
Gene Type | protein-coding |
Description | ecotropic viral integration site 5 |
Other Description | EVI-5|dJ846D11.1 (ecotropic viral integration site 5)|ecotropic viral integration site 5 protein homolog|neuroblastoma stage 4S gene protein |
Swissprots | B9A6J0 Q9H1Y9 O60447 A6NKX8 |
Accessions | O60447 AA725529 AB209513 BAD92750 AB449875 BAH16618 AF008915 AAC16031 BC141544 AAI41545 BC156793 AAI56794 BP282704 CN334472 XM_011542099 XP_011540401 XM_011542100 XP_011540402 XM_011542101 XP_011540403 XM_011542102 XP_011540404 XM_011542103 XP_011540405 XM_011542104 XP_011540406 XM_011542105 XP_011540407 XM_011542106 XP_011540408 XM_011542107 XP_011540409 XM_011542108 XP_011540410 XM_011542109 XP_011540411 XM_011542110 XP_011540412 XM_011542111 XP_011540413 NM_001308248 NP_001295177 NM_005665 NP_005656 |
Function | Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis. {ECO:0000269|PubMed:16439210}. |
Subcellular Location | Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associates with the mitotic spindle through anaphase and remains within the midzone and midbody until completion of cytokinesis. |
Tissue Specificity | Expressed in various cell lines (at protein level). Expressed in a wide range of tissues including brain and adrenal. {ECO:0000269|PubMed:16033705, ECO:0000269|PubMed:9618176}. |
EVI5 CRISPR/Cas9 KO Plasmid (h) - sc-407739 from Santa Cruz Biotechnology
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EVI5 HDR Plasmid (h) - sc-407739-HDR from Santa Cruz Biotechnology
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EVI5 Double Nickase Plasmid (h) - sc-407739-NIC from Santa Cruz Biotechnology
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EVI5 Double Nickase Plasmid (h2) - sc-407739-NIC-2 from Santa Cruz Biotechnology
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EVI5 CRISPR Activation Plasmid (h) - sc-407739-ACT from Santa Cruz Biotechnology
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EVI5 CRISPR Activation Plasmid (h2) - sc-407739-ACT-2 from Santa Cruz Biotechnology
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EVI5 Lentiviral Activation Particles (h) - sc-407739-LAC from Santa Cruz Biotechnology
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EVI5 Lentiviral Activation Particles (h2) - sc-407739-LAC-2 from Santa Cruz Biotechnology
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EVI5 siRNA (h) - sc-78845 from Santa Cruz Biotechnology
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EVI5 shRNA Plasmid (h) - sc-78845-SH from Santa Cruz Biotechnology
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EVI5 shRNA (h) Lentiviral Particles - sc-78845-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU027381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8021 from Sigma-Aldrich
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EVI5 siRNA (Human) - CRH5284 from Cohesion Biosciences
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EVI5 - MBS8214907 from MyBioSource
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shRNA set against Human EVI5 (NM_005665.4) - SHH287797 from Creative biogene
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shRNA set against Human EVI5(NM_005665.4) - SHH040979 from Creative biogene
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Human EVI5 siRNA - orb265786 from Biorbyt
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EVI5 shRNA Plasmid (Human) - CHH5284 from Cohesion Biosciences
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EVI5 miRNA 3'UTR clone - MiUTR1H-03330 from Creative biogene
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