GPC6

Gene Symbol GPC6
Entrez Gene 10082
Alt Symbol OMIMD1
Species Human
Gene Type protein-coding
Description glypican 6
Other Description glypican proteoglycan 6|glypican-6
Swissprots Q96SG5 A8K279 Q9H1P4 Q9Y625 Q96SG8
Accessions EAX08931 EAX08932 EAX08933 EAX08934 Q9Y625 AF105267 AAD55749 AF111178 AAD31392 AK074741 AK130013 AK290144 BAF82833 AK304338 BAG65183 AY358462 AAQ88827 BC106947 AAI06948 BQ009005 BQ182216 BX640888 XM_011521044 XP_011519346 NM_005708 NP_005699
Function Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases (By similarity). Enhances migration and invasion of cancer cells through WNT5A signaling. {ECO:0000250, ECO:0000269|PubMed:21871017}.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}.
Tissue Specificity Widely expressed. High expression in fetal kidney and lung and lower expressions in fetal liver and brain. In adult tissues, very abundant in ovary, high levels also observed in liver, kidney, small intestine and colon. Not detected in peripheral blood leukocytes. Detected in breast cancer cells (at protein level). {ECO:0000269|PubMed:10480909, ECO:0000269|PubMed:21871017}.

glypican-6 CRISPR/Cas9 KO Plasmid (h) - sc-405359 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-6 HDR Plasmid (h) - sc-405359-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-6 Double Nickase Plasmid (h) - sc-405359-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-6 Double Nickase Plasmid (h2) - sc-405359-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-6 CRISPR Activation Plasmid (h) - sc-405359-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-6 CRISPR Activation Plasmid (h2) - sc-405359-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-6 Lentiviral Activation Particles (h) - sc-405359-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-6 Lentiviral Activation Particles (h2) - sc-405359-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-6 siRNA (h) - sc-75152 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

glypican-6 shRNA Plasmid (h) - sc-75152-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

glypican-6 shRNA (h) Lentiviral Particles - sc-75152-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU002631 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9518 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9518 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04920 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04920

GPC6 siRNA (Human) - CRH6792 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPC6 - MBS829898 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GPC6 (NM_005708.3) - SHH305798 from Creative biogene

Category siRNA
Species Reactivities Human

Human GPC6 siRNA - orb267294 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPC6 shRNA Plasmid (Human) - CHH6792 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GPC6 miRNA 3'UTR clone - MiUTR4H-TG11352 from Creative biogene

Species Reactivities Human
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